Inflammatory Bowel Disease: From Bench to Bedside

abdominal abscesses absorption acute afferent antibodies antigens arachidonic acid arthritis associated bacterial biopsy chronic clinical colectomy colitis and Crohn's collagen colon colonoscopy complications Crohn's colitis Crohn's disease cytokines develop diagnosis diarrhea disease activity distal dysplasia ease effects eicosanoids electrolyte endoscopic epithelial cells extraintestinal fistulas function Gastroenterology gastrointestinal genes genetic granulomas growth factor human ileal ileum immune Immunol increased infection inflammation inflammatory bowel disease inhibit interleukin involvement lamina propria lesions lymphocytes macrophages matory bowel disease mechanisms mediators metabolites mucosal neurons neutrophils nociceptive normal pain pathogenesis patients with Crohn's patients with IBD patients with ulcerative peptide peripheral proctitis production prostaglandin protein reactive receptor rectal rectum reported resection response risk role Scand J Gastroenterol sclerosing cholangitis secretion small bowel small intestine smooth muscle stimulation strictures studies sulfasalazine surgery symptoms syndrome synthesis therapy tients tion tissue toxic toxic megacolon tract treatment ulcerative colitis