Fine Structure of Proteins and Nucleic Acids

a-lactalbumin absorption Acta adenine adenosine amino acid aromatic atom band base protons binding Biochem Biochemistry Biol Biophys Brahms buried calculated carboxyl Chem chemical shifts chromophore circular dichroism Co² complex concentration conformational change Cotton effect curve cytidine cytosine D₂O denaturation dichroic difference dimer dipole electronic enzyme experimental exposure fluorescence formation glycol guanosine helical histidine hydrogen bonding indicate inosine interaction ionization lysozyme magnetic measurements methyl Michelson model compound molar molecular monomer myoglobin native protein nucleic acid nucleosides observed obtained oxidation phosphate PMR spectra polarizability poly polymer polynucleotides positive Proc protein protein molecule protons purine pyrimidine pyrimidine nucleosides random-coil reaction reactivity reagent region residues ribonuclease ring ring-current rotational strength Scheraga Section side chains solvent perturbation spectrum stacking structure studies Table technique temperature Tinoco titration transition tryptophan tyrosine tyrosyl groups uracil urea uridine values wavelength X-ray