Population Genetics: A Concise GuideThis concise introduction offers students and researchers an overview of the discipline that connects genetics and evolution. Addressing the theories behind population genetics and relevant empirical evidence, John Gillespie discusses genetic drift, natural selection, nonrandom mating, quantitative genetics, and the evolutionary advantage of sex. First published to wide acclaim in 1998, this brilliant primer has been updated to include new sections on molecular evolution, genetic drift, genetic load, the stationary distribution, and two-locus dynamics. This book is indispensable for students working in a laboratory setting or studying free-ranging populations. |
Contents
Genetic Variation | 1 |
Genetic Drift | 21 |
Natural Selection | 59 |
TwoLocus Dynamics | 104 |
Nonrandom Mating | 120 |
5 | 130 |
Quantitative Genetics | 142 |
4 | 154 |
The Evolutionary Advantage of | 170 |
4 | 179 |
Appendix A Mathematical Necessities | 185 |
| 207 | |
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Common terms and phrases
A₁ allele additive variance allele frequency amino acid ancestor approximation assumption average B₁ balancing selection called chapter coalescent correlation covariance deleterious alleles deleterious mutations derivation diploid distribution dominance Drosophila melanogaster dynamics environment epistasis Equation equilibrium estimate example fixation probability function gametes genetic drift genetic load genetic variation genome genotype frequencies Hardy-Weinberg law heritability heterozygote heterozygous heterozygous effect hitchhiking homozygotes homozygous identical by descent illustrated in Figure inbred individual intensity of selection lethal mutation lineage loci locus mean fitness mean number molecular evolution Muller's ratchet mutation rate natural populations natural selection neutral theory nucleotide number of deleterious number of mutations obtained occurs outbred overdominance paracone height phenotype Poisson polymorphism population genetics Problem protein quantitative genetics quantitative traits random mating random variable rate of substitution recombination sample second chromosome segregating sites selection coefficient stochastic Var{p viability Wright-Fisher model zero
Popular passages
Page x - Kimura, M. and Ohta, T. (1971) 'Protein Polymorphism as a Phase of Molecular Evolution', Nature 229, 467^69.
Page x - Deleterious Mutations and the Evolution of Sexual Reproduction', Nature 336: 435—440.
Page ix - There is no better example than genetic drift, the small random changes in genotype frequencies caused by variation in offspring number between individuals and, in diploids, genetic segregation.