Journal of the National Cancer Institute: Monographs, Issue 11

adjuvant chemotherapy adjuvant tamoxifen adjuvant therapy analysis aneuploid assessment axillary nodes benefit breast cancer patients Breast Cancer Study breast carcinoma breast conservation breast recurrence Cancer Inst Monogr Cancer Institute Cancer Study Group cathepsin D Clin Oncol clinical trial CMFP compared control group disease disease-free survival early breast cancer EGFr Engl ER-negative ER-positive estrogen receptor evaluation FISHER flow cytometry fluorouracil hazard ratio Hospital irradiation lumpectomy lymph nodes margins median follow-up menopausal metastases methotrexate months National Surgical Adjuvant Natl Cancer Inst negative node-negative breast cancer node-negative patients node-positive NSABP nuclear grade number of patients observed oncologists Oncology overall survival pathologic patients treated ploidy postmenopausal primary breast cancer primary tumor prognostic factors protocol Q-TWIST quality-adjusted radiation therapy radiotherapy randomized trials recurrence rate relapse risk S-phase fraction significant subgroups systemic therapy Table tamoxifen tients tion tive total mastectomy toxic treatment effect women