Antibiotic-impregnated Vascular GraftsVascular grafts infections persist despite advances in graft materials and new, potent antibodies. The consequences of these infections - loss of limb or loss of life are the main significant problems. Antibiotic-bonded grafts provide protection against infections during the period of greatest vulnerability - the initial weeks following implantation. Experimental results demonstrate gradual improvement in the efficacy of these grafts. |
Contents
Current Status | 1 |
Bacteriology and Pathogenesis of Graft | 23 |
Antibiotics Used in the Prophylaxis | 38 |
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Common terms and phrases
abdominal amikacin aminoglycosides anastomosis anastomotic Ann Surg antibacterial antibiotic activity antibiotic bonding antibiotic-bonded antimicrobial aorta aortic graft infection Arch Surg arterial grafts bacteremia bacteremic infection Bandyk binding blood bonded graft bypass graft canine model cefazolin cefoxitin cephalosporins ciprofloxacin coli collagen colleagues contamination Dacron grafts diagnosis distal elution endothelial cells epidermidis experiments extraanatomic bypass false aneurysms femoral artery fibrin fluoroquinolones graft implantation graft material graft surface gram-negative gram-positive Greco groin hematogenous ideal graft incidence infected graft intraabdominal intravenous investigators involved ionic bonding method Moore WS organisms oxacillin patients pefloxacin penicillins perigraft perioperative polytetrafluoroethylene postoperative preclotted present prophylactic prophylaxis prosthetic graft infection prosthetic vascular graft proteins PTFE PTFE grafts reported resistance revascularization rifampin scan sepsis soaking Staphylococcus aureus surgical TDMAC techniques tion tissue tobramycin treated grafts treatment untreated Vasc Surg 1991 vascular graft infections vascular prosthesis vascular prosthetic infection vascular surgery velour versus vitro vivo