Clinical Genomics: Practical Applications for Adult Patient Care

Front Cover
McGraw Hill Professional, Oct 22, 2013 - Medical - 608 pages
Convert the latest genomic data to the most effective patient management and treatment approaches

Clinical Genomics helps healthcare providers translate the vast amount of new genomic data into successful clinical application. It is a comprehensive textbook and practical guide to the use of this information across a broad spectrum of adult diseases – from individual differences in drug responses, cardiac and cancer risks to Alzheimer's and other neurological and psychiatric disorders.

While traditional textbooks on medical genetics focus on classic Mendelian disorders, Clinical Genomics discusses the everyday application of genetic assessment and the diagnostic, therapeutic, and preventive implications to the most common adult diseases that healthcare providers encounter. Covering approximately 200 conditions, it is a true clinical text for use across all of internal medicine.

Coverage of each condition is presented in a consistent, clinically relevant manner and includes:

  • Key Points
  • Diagnostic Criteria and Clinical Characteristics
  • Screening and C ounseling
  • Management and Treatment
  • Molecular Genetics and Molecular Mechanism
  • Supplementary Information

More than ten valuable appendices, include Genetic Privacy; Race, Ancestry, and Genetics; Personalized Medicine in Clinical Practice; Clinical Interpretation of Genomic Data; and Genetic Risk Profiling in the Genomics Era.

Clinical Genomics is essential for internists, primary care physicians, and other healthcare providers who wish to increase their knowledge of the gene-and-protein level care of patients in a clinical setting.

From inside the book

 

Contents

Concepts and Strategies
1
Pharmacogenetics
7
Cardiovascular Disease
49
Copyright

20 other sections not shown

Other editions - View all

Clinical Genomics: Practical Applications for Adult Patient Care
Michael F. Murray (Physician),Mark Babyatski, MD,Monica A. Giovanni,Fowzan S. Alkuraya,Douglas R. Stewart
Snippet view - 2013

Common terms and phrases

abacavir abnormalities acid activity acute adrenal adults affected allele amyloidosis anemia aneurysm aortic asymptomatic autosomal dominant autosomal recessive blood cancer carcinoma cardiac cardiomyopathy carnitine carriers cause cell chromosome chronic Clin Clinical Characteristics clopidogrel common Counseling Screening Criteria and Clinical defects deficiency deletions diabetes Diagnostic Criteria Differential diagnosis Disease summary disorders dose drug encodes enzyme evaluation family history fibrosis function genetic testing Genome-wide associations genomic genotype glucose GWAS hepatic hereditary hormone HSCR hypertension hypoglycemia identified increased risk individuals infection Information oMiM references inherited inhibitor insulin kinase levels Management and Treatment Medical Medicine MEN1 metabolism Molecular Genetics mutations normal obesity oMiM onset pancreatic pathway patients Pharmacogenetics phenotype pituitary plasma polymorphisms porphyria pre-eclampsia pregnancy protein psoriasis receptor renal risk factors sarcoidosis Screening and Counseling serum SNPs statin studies Supplementary Information oMiM susceptibility symptoms syndrome Table tamoxifen therapy thrombophilia thyroid tion TPMT tumors variable variants warfarin

About the author (2013)

Michael Murray, MD is Director of the Division of Clinical Genetics at Harvard University School of Medicine, one of the premier genetics research institutions in the world.

Mark Babyatski, MD is Director of the Internal Medicine Residency program. Mount Sinai School of Medicine, New York NY

Bibliographic information

TitleClinical Genomics: Practical Applications for Adult Patient Care
AuthorsMichael T. Murray, Mark Babyatski, Monica Giovanni
PublisherMcGraw Hill Professional, 2013
ISBN0071810595, 9780071810593
Length608 pages
Subjects › 

Medical / Genetics
  
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