The Framingham diet study: diet and the regulation of serum cholesterol

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U.S. Department of Health, Education, and Welfare, National Institutes of Health, 1971 - Cardiovascular system - 78 pages
Abstract: Data from an epidemiological investigation of cardiovascular disease is presented in a National Institutes of Health report which examines the role of diet in regulation of serum cholesterol. Diet assessment of a sample of 912 subjects from the Framington study cohort was conduced over 36 months using dietary interviews. The data, summarized in tabular form, demonstates no association between long-term intakes of fat, protein, or dietary cholesterol with serum cholesterol level; nor was any relation observed betwwen serum cholesterol and either the ratio of plant to animal fat, or the ratio of complex to simple carbohydrates. A weak negative correlation between caloric intake and serum cholesterol level was observed in men, but not in women. Thus, this study fails to point out any positive association between dietary characteristics and serum cholesterol. However, the data suggests that energy balance, rather than diet, may be important. No indication of any relationship between diet and subsequent development of coronary heart disease exists for this study group.

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