Advanced Therapy of Inflammatory Bowel Disease, Volume 2: IBD and Crohn's DiseaseNow published in two volumes to accommodate new chapters on the many advances in understanding and treatment options, this set of volumes represents the definitive reference on inflammatory bowel disease, a spectrum of diseases that is receiving increasing attention as our understanding of the etiological factors increases and diagnostic tools are refined. Basic research accelerated at the beginning of this decade and is now yielding new, more targeted treatments than were available just a few years ago. Volume 1 is on IBD and Ulcerative Colitis, and Volume 2 is on IBD and Crohn's Disease. All areas that were covered in the 2nd edition have been expanded and updated. New sections include the rapidly expanding knowledge of genetics and the role of the intestinal flora and environmental factors in etiology and pathogenesis. Among the 168 chapters, there are 20 on biologic therapies and 30 on surgical management. The consultant/authors clearly state their approach to important issues, such as the duration of immunomodulator and of anti-TNF-a use and the options for managing isolated low-grade dysplasia. A strong focus on the individual patient is woven throughout both volumes, including the benefits and risks of potentially life-altering therapies and surgeries. Entire sections detail concerns about the well-being of each person. This book provides information for health professionals who help both pediatric and adult patients navigate through the lifelong shadow of a chronic, probably genetically determined ordeal. |
Contents
615 | |
621 | |
Treatment of Crohns Disease | 673 |
StepUp Versus TopDown Therapy in the EvidenceBased Results | 683 |
The Role of Mesalamine in AntiTNF Therapy | 693 |
Topically Active Steroid and Biologics in Crohns Disease | 699 |
Optimizing Azathioprine Therapy in Adolescents | 711 |
SURGERY FOR CROHNS | 723 |
Colonoscopic Screening and Surveillance 138 Clinical Management | 851 |
Small Bowel Stenosis in 139 Intestinal Transplantation | 859 |
Colonic Strictures | 867 |
Keely Parisian and Bret A Lashner 141 Surgery for Crohns Colitis | 873 |
Clinical Practice in IBDThe Role of Uma Mahadevan | 897 |
Pediatric Patient | 903 |
Sexual Adjustments and Syndromes Affecting the Gastrointestinal Tract 993 | 913 |
Exaggaerated and Index 1021 | 935 |
Impact on Surgical Management 829 | 759 |
Crohns Jejunoileitis 767 136 Measures to Minimize Postoperative | 839 |
Management of Internal and External Paul J Rutgeerts | 845 |
Stress Management | 941 |
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Common terms and phrases
6-mercaptopurine abdominal abscess acid active Crohn's disease adalimumab adverse events Aliment Pharmacol Ther anastomosis anti-TNF agent anti-TNF therapy antibiotics antibodies associated azathioprine biologic therapy budesonide CD patients cell certolizumab certolizumab pegol chronic clinical remission clinical response colon combination therapy complications controlled trial corticosteroids Crohn's disease cyclosporine diagnosis diarrhea dose drug Editor's note TMB effects efficacy endoscopic Engl enteral nutrition enteroscopy evaluation factors fistula Gastroenterology gastrointestinal HSTCL ileal ileum immunomodulators immunosuppressive improvement increased induction infections Inflamm Bowel inflammatory bowel disease infliximab infusion laparoscopic long-term lymphoma mesalamine methotrexate mg/kg mucosal healing natalizumab oral outcomes pain parenteral patients with Crohn's pediatric pegol perianal placebo postoperative randomized recurrence relapse remission rates resection risk Rutgeerts Sandborn WJ short bowel syndrome small bowel steroids strictureplasty strictures surgery surgical symptoms therapeutic thiopurine tion treatment of Crohn's ulcerative colitis versus vitamin weeks