Inflammatory Bowel DiseaseJoseph B. Kirsner, Roy Gerrard Shorter This text is intended to help provide the practical perspectiv= e practitioners need to manage patients suffering from inflammatory bowel disease. This fourth edition contains 11 new chapters and is illustrated with photographs and detailed line drawings. |
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Page 87
... mice have a defect in the LPS locus on chromosome 4. It was noted that some of the mice in the production colony at Jackson Laboratories developed diarrhea and perianal ulcers . These mice were inbred to de- velop a substrain that has a ...
... mice have a defect in the LPS locus on chromosome 4. It was noted that some of the mice in the production colony at Jackson Laboratories developed diarrhea and perianal ulcers . These mice were inbred to de- velop a substrain that has a ...
Page 89
... mice . These findings sug- gest that colitis in these T - cell mutant mice re- quire both the presence of mature functioning B lymphocytes and the absence of class II MHC - restricted CD4 + aß T cells . The colitis thus may be caused by ...
... mice . These findings sug- gest that colitis in these T - cell mutant mice re- quire both the presence of mature functioning B lymphocytes and the absence of class II MHC - restricted CD4 + aß T cells . The colitis thus may be caused by ...
Page 90
... mice is caused by any spe- cific contagious pathogen . Nevertheless , there appears to be a role for commensal microor- ganisms in the induction of the disease , since IL - 2 - deficient mice bred in a completely germfree environment do ...
... mice is caused by any spe- cific contagious pathogen . Nevertheless , there appears to be a role for commensal microor- ganisms in the induction of the disease , since IL - 2 - deficient mice bred in a completely germfree environment do ...
Contents
Historical Antecedents of Inflammatory | 3 |
The Epidemiology of Idiopathic Inflammatory | 31 |
Naturally Occurring and Experimental Models | 71 |
Copyright | |
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Common terms and phrases
abnormalities acid activity acute altered antibodies antigens appear areas associated bacterial biopsies blood cancer carcinoma cause cells changes chronic Clin clinical coli colon common compared complications controls Crohn's disease cytokines demonstrated develop diagnosis diarrhea dysplasia ease effects enteritis epithelial cells epithelium et al evidence examination expression factor Figure findings fistulas function Gastroenterol Gastroenterology gene genetic growth human identified ileum immune important incidence increased indicate induced infection inflammation inflammatory bowel disease initial intestinal involved lamina propria lesions less levels lymphocytes major mechanisms mediators mucosal neutrophils normal observed occur patients patients with Crohn's population possible present production protein rats recent receptor rectal rectum regional relatives reported response risk role severe similar small bowel specific strictures studies suggest symptoms Table therapy tients tion tissue tive treatment ulcerative colitis usually