Water and Biological MacromoleculesWesthof Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging. Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists. |
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Page 72
... ( Figure 3.4 ) . The peaks in the phi distributions show that the water molecules are mainly clustered around + 90 ° and -90 ° , i.e. directly below and directly above the plane containing the C , N and CA atoms . The very few solvent ...
... ( Figure 3.4 ) . The peaks in the phi distributions show that the water molecules are mainly clustered around + 90 ° and -90 ° , i.e. directly below and directly above the plane containing the C , N and CA atoms . The very few solvent ...
Page 138
... Figure 4.7 has been published in Acta Crystal- lographica and is reproduced by permission of the International Union of Crystallography . Figure 4.15 has been published in Advances in Protein Chemistry and is reproduced by permission of ...
... Figure 4.7 has been published in Acta Crystal- lographica and is reproduced by permission of the International Union of Crystallography . Figure 4.15 has been published in Advances in Protein Chemistry and is reproduced by permission of ...
Page 250
... ( Figure 8.1 ) . ( 3 ) Whatever the sequence and the form a water molecule bridges the purine N , or the pyrimidine O2 atom to O , ' oxygen of the following residue in the minor groove ( Figure 8.2 ) . ( 4 ) A large number of base . base ...
... ( Figure 8.1 ) . ( 3 ) Whatever the sequence and the form a water molecule bridges the purine N , or the pyrimidine O2 atom to O , ' oxygen of the following residue in the minor groove ( Figure 8.2 ) . ( 4 ) A large number of base . base ...
Contents
Water structure | 3 |
Thermodynamic and dynamic properties of water | 45 |
Aqueous solutions of simple hydrophobic solutes | 55 |
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Acta Cryst analysis anionic aqueous atoms B-DNA B-form backbone base pairs Beveridge binding Biochemistry Biochim Biol Biomol Biophys Biopolymers calculations Cevc chain Chem Clementi complex conformation counterions crystal structure crystalline crystallographic d(CGCGAATTCGCG density distance dodecamer electron electrostatic Equation experimental Figure force field free energy function Gibbs energy Goodfellow H-bond helix hydration hydration forces hydration shell hydrogen bonds hydrophilic hydrophobic ice Ih interactions interfacial ions lipid bilayers lipid headgroups liquid macromolecules MD simulation membrane minor groove mJ/m² molecular dynamics Molecular dynamics simulation Monte Carlo neutron diffraction nucleic acids nucleotide orientation oxygen phase phosphate groups phosphatidylcholine phospholipid Phys polar polymer polysaccharides potential refinement region relaxation repulsive residues resolution Saenger side-chains solution solvation solvation Gibbs energy solvent solvent molecules solvent structure ẞ-sheet stability Struct studies surface temperature tion water bridges water molecules water structure Westhof X-ray Z-DNA