Water and Biological MacromoleculesWesthof Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging. Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists. |
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Page 192
... base - pair opening on the picosecond time - scale . Extensive Monte Carlo equilibration of the solvent was used to ... base pairs . The DNA base pairs show a consistent inclination in the simulation , in accord with the interpretation ...
... base - pair opening on the picosecond time - scale . Extensive Monte Carlo equilibration of the solvent was used to ... base pairs . The DNA base pairs show a consistent inclination in the simulation , in accord with the interpretation ...
Page 228
... BASE BRIDGES B - DNA : methyl ・・・ Ow ・・・ phosphate • A - DNA and RNA : N7 ( purines ) .・・ Ow ・・・ phosphate Purine in syn : External Gsyn - Canti base pairs in Z - DNA Ganti - Asyn and Gsyn - Aanti in B - DNA 3 ' - PHOSPHATE ...
... BASE BRIDGES B - DNA : methyl ・・・ Ow ・・・ phosphate • A - DNA and RNA : N7 ( purines ) .・・ Ow ・・・ phosphate Purine in syn : External Gsyn - Canti base pairs in Z - DNA Ganti - Asyn and Gsyn - Aanti in B - DNA 3 ' - PHOSPHATE ...
Page 235
... base pair ( via N1 and 06 of the guanine bases ) is strengthened by a water bridge linking the amino group N2 of one base and the 06 of the other . Besides those additional base - water - base bridges across the pair , unusual base ...
... base pair ( via N1 and 06 of the guanine bases ) is strengthened by a water bridge linking the amino group N2 of one base and the 06 of the other . Besides those additional base - water - base bridges across the pair , unusual base ...
Contents
Water structure | 3 |
Thermodynamic and dynamic properties of water | 45 |
Aqueous solutions of simple hydrophobic solutes | 55 |
Copyright | |
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Acta Cryst analysis anionic aqueous atoms B-DNA B-form backbone base pairs Beveridge binding Biochemistry Biochim Biol Biomol Biophys Biopolymers calculations Cevc chain Chem Clementi complex conformation counterions crystal structure crystalline crystallographic d(CGCGAATTCGCG density distance dodecamer electron electrostatic Equation experimental Figure force field free energy function Gibbs energy Goodfellow H-bond helix hydration hydration forces hydration shell hydrogen bonds hydrophilic hydrophobic ice Ih interactions interfacial ions lipid bilayers lipid headgroups liquid macromolecules MD simulation membrane minor groove mJ/m² molecular dynamics Molecular dynamics simulation Monte Carlo neutron diffraction nucleic acids nucleotide orientation oxygen phase phosphate groups phosphatidylcholine phospholipid Phys polar polymer polysaccharides potential refinement region relaxation repulsive residues resolution Saenger side-chains solution solvation solvation Gibbs energy solvent solvent molecules solvent structure ẞ-sheet stability Struct studies surface temperature tion water bridges water molecules water structure Westhof X-ray Z-DNA