Water and Biological MacromoleculesWesthof Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging. Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists. |
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Page 208
... complex was carried out using MC simula- tion and thermodynamic perturbation theory ( Jayaram et al . , 1991 ) . The system considered in this project was the dimer of the amino - terminal fragment of the λ repressor in a complex with a ...
... complex was carried out using MC simula- tion and thermodynamic perturbation theory ( Jayaram et al . , 1991 ) . The system considered in this project was the dimer of the amino - terminal fragment of the λ repressor in a complex with a ...
Page 330
... complex type glycan ( Montreuil , 1980 ; Spik et al . , 1982 ) ( Figure 11.8 ) . The TRI conformation in the LOL I / TRI complex is very close to that of unbound TRI ( Warin et al . , 1979 ) . In contrast to the direct interaction of ...
... complex type glycan ( Montreuil , 1980 ; Spik et al . , 1982 ) ( Figure 11.8 ) . The TRI conformation in the LOL I / TRI complex is very close to that of unbound TRI ( Warin et al . , 1979 ) . In contrast to the direct interaction of ...
Page 334
... complex , is strikingly confirmed in the phosphorylase b glycogen storage site complexes to maltoheptaose and in LOL I - TRI or LOL I - OCTA complexes . Two examples show an extreme and compara- ble pattern : the glycogen storage minor ...
... complex , is strikingly confirmed in the phosphorylase b glycogen storage site complexes to maltoheptaose and in LOL I - TRI or LOL I - OCTA complexes . Two examples show an extreme and compara- ble pattern : the glycogen storage minor ...
Contents
Water structure | 3 |
Thermodynamic and dynamic properties of water | 45 |
Aqueous solutions of simple hydrophobic solutes | 55 |
Copyright | |
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Acta Cryst analysis anionic aqueous atoms B-DNA B-form backbone base pairs Beveridge binding Biochemistry Biochim Biol Biomol Biophys Biopolymers calculations Cevc chain Chem Clementi complex conformation counterions crystal structure crystalline crystallographic d(CGCGAATTCGCG density distance dodecamer electron electrostatic Equation experimental Figure force field free energy function Gibbs energy Goodfellow H-bond helix hydration hydration forces hydration shell hydrogen bonds hydrophilic hydrophobic ice Ih interactions interfacial ions lipid bilayers lipid headgroups liquid macromolecules MD simulation membrane minor groove mJ/m² molecular dynamics Molecular dynamics simulation Monte Carlo neutron diffraction nucleic acids nucleotide orientation oxygen phase phosphate groups phosphatidylcholine phospholipid Phys polar polymer polysaccharides potential refinement region relaxation repulsive residues resolution Saenger side-chains solution solvation solvation Gibbs energy solvent solvent molecules solvent structure ẞ-sheet stability Struct studies surface temperature tion water bridges water molecules water structure Westhof X-ray Z-DNA