Water and Biological MacromoleculesWesthof Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging. Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists. |
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Page 32
... density in the 279 K and neutron structure of coenzyme B12 . Solvent density is obtained from a F.-F. difference Fourier synthesis in which the solvent was omitted from the phases . The main water density and positions are projected ...
... density in the 279 K and neutron structure of coenzyme B12 . Solvent density is obtained from a F.-F. difference Fourier synthesis in which the solvent was omitted from the phases . The main water density and positions are projected ...
Page 46
... Density and Isothermal Compressibility of Liquid Water for Figure 2.1 gives the particle number densities at saturation vapour pressure for light and heavy water . Both liquids exhibit a temperature of maximum density , TMD ( see insert ...
... Density and Isothermal Compressibility of Liquid Water for Figure 2.1 gives the particle number densities at saturation vapour pressure for light and heavy water . Both liquids exhibit a temperature of maximum density , TMD ( see insert ...
Page 108
... density to the protein model beyond a preset distance from any surface protein atom , with a smoothing function used ... density map of the water structure within insulin crys- tals ( 67 % v / v of solvent : Badger and Caspar , 1991 ) ...
... density to the protein model beyond a preset distance from any surface protein atom , with a smoothing function used ... density map of the water structure within insulin crys- tals ( 67 % v / v of solvent : Badger and Caspar , 1991 ) ...
Contents
Water structure | 3 |
Thermodynamic and dynamic properties of water | 45 |
Aqueous solutions of simple hydrophobic solutes | 55 |
Copyright | |
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Acta Cryst analysis anionic aqueous atoms B-DNA B-form backbone base pairs Beveridge binding Biochemistry Biochim Biol Biomol Biophys Biopolymers calculations Cevc chain Chem Clementi complex conformation counterions crystal structure crystalline crystallographic d(CGCGAATTCGCG density distance dodecamer electron electrostatic Equation experimental Figure force field free energy function Gibbs energy Goodfellow H-bond helix hydration hydration forces hydration shell hydrogen bonds hydrophilic hydrophobic ice Ih interactions interfacial ions lipid bilayers lipid headgroups liquid macromolecules MD simulation membrane minor groove mJ/m˛ molecular dynamics Molecular dynamics simulation Monte Carlo neutron diffraction nucleic acids nucleotide orientation oxygen phase phosphate groups phosphatidylcholine phospholipid Phys polar polymer polysaccharides potential refinement region relaxation repulsive residues resolution Saenger side-chains solution solvation solvation Gibbs energy solvent solvent molecules solvent structure ẞ-sheet stability Struct studies surface temperature tion water bridges water molecules water structure Westhof X-ray Z-DNA