Water and Biological MacromoleculesWesthof Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging. Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists. |
From inside the book
Results 1-3 of 37
Page 179
... grooves of a B - DNA structure , the calculated results correspond closely to the estimates from solvent accessibility calculations by Alden and Kim ( 1979 ) . · Results on the calculated hydration density in the minor groove are shown ...
... grooves of a B - DNA structure , the calculated results correspond closely to the estimates from solvent accessibility calculations by Alden and Kim ( 1979 ) . · Results on the calculated hydration density in the minor groove are shown ...
Page 181
... groove , the calculated saturation of hydrophilic binding sites with waters of hydration in the calculation corresponds closely to the crystallographic results . The 16 K structure and the MPD7 structure show evidence for some various ...
... groove , the calculated saturation of hydrophilic binding sites with waters of hydration in the calculation corresponds closely to the crystallographic results . The 16 K structure and the MPD7 structure show evidence for some various ...
Page 250
... groove 06 ( G ) ... W .. · N4 ( C ) B Ꮓ 2 O2 ( T ) . . .W .. · O2 ( T ) None 06 ( G ) ... W .. · 06 ( G ) None N4 ( C )・・・ W · · · O4 ( T ) 06 ( G ) · · · W · · · O4 ( T ) O4 ( T ) · · · W · · · O4 ( T ) previous analysis some general ...
... groove 06 ( G ) ... W .. · N4 ( C ) B Ꮓ 2 O2 ( T ) . . .W .. · O2 ( T ) None 06 ( G ) ... W .. · 06 ( G ) None N4 ( C )・・・ W · · · O4 ( T ) 06 ( G ) · · · W · · · O4 ( T ) O4 ( T ) · · · W · · · O4 ( T ) previous analysis some general ...
Contents
Water structure | 3 |
Thermodynamic and dynamic properties of water | 45 |
Aqueous solutions of simple hydrophobic solutes | 55 |
Copyright | |
43 other sections not shown
Other editions - View all
Common terms and phrases
Acta Cryst analysis anionic aqueous atoms B-DNA B-form backbone base pairs Beveridge binding Biochemistry Biochim Biol Biomol Biophys Biopolymers calculations Cevc chain Chem Clementi complex conformation counterions crystal structure crystalline crystallographic d(CGCGAATTCGCG density distance dodecamer electron electrostatic Equation experimental Figure force field free energy function Gibbs energy Goodfellow H-bond helix hydration hydration forces hydration shell hydrogen bonds hydrophilic hydrophobic ice Ih interactions interfacial ions lipid bilayers lipid headgroups liquid macromolecules MD simulation membrane minor groove mJ/m² molecular dynamics Molecular dynamics simulation Monte Carlo neutron diffraction nucleic acids nucleotide orientation oxygen phase phosphate groups phosphatidylcholine phospholipid Phys polar polymer polysaccharides potential refinement region relaxation repulsive residues resolution Saenger side-chains solution solvation solvation Gibbs energy solvent solvent molecules solvent structure ẞ-sheet stability Struct studies surface temperature tion water bridges water molecules water structure Westhof X-ray Z-DNA