Water and Biological MacromoleculesWesthof Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging. Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists. |
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Page 149
... Hydrogen Bonding in a - helices +4 The a - helix is stabilized by sequential 1-5 hydrogen bonds between the main chain CO , and NH ; + groups . These main - chain groups can also be involved in additional hydrogen bonds particularly to ...
... Hydrogen Bonding in a - helices +4 The a - helix is stabilized by sequential 1-5 hydrogen bonds between the main chain CO , and NH ; + groups . These main - chain groups can also be involved in additional hydrogen bonds particularly to ...
Page 152
... Hydrogen Bonds The insertion of a water molecule into a 1-5 hydrogen bond causes noticeable changes in the local helix structure by disrupting several other adjacent 1-5 helix hydrogen bonds15 ( Figure 5.4 ) . When the water mol- ecule ...
... Hydrogen Bonds The insertion of a water molecule into a 1-5 hydrogen bond causes noticeable changes in the local helix structure by disrupting several other adjacent 1-5 helix hydrogen bonds15 ( Figure 5.4 ) . When the water mol- ecule ...
Page 334
... hydrogen bonds are the main factors in conferring specificity and affinity to protein- carbohydrate interactions ' . As a result , ' all the polar groups of the monopyrannoside substrates are involved in hydrogen bonding ' . For the ...
... hydrogen bonds are the main factors in conferring specificity and affinity to protein- carbohydrate interactions ' . As a result , ' all the polar groups of the monopyrannoside substrates are involved in hydrogen bonding ' . For the ...
Contents
Water structure | 3 |
Thermodynamic and dynamic properties of water | 45 |
Aqueous solutions of simple hydrophobic solutes | 55 |
Copyright | |
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Acta Cryst analysis anionic aqueous atoms B-DNA B-form backbone base pairs Beveridge binding Biochemistry Biochim Biol Biomol Biophys Biopolymers calculations Cevc chain Chem Clementi complex conformation counterions crystal structure crystalline crystallographic d(CGCGAATTCGCG density distance dodecamer electron electrostatic Equation experimental Figure force field free energy function Gibbs energy Goodfellow H-bond helix hydration hydration forces hydration shell hydrogen bonds hydrophilic hydrophobic ice Ih interactions interfacial ions lipid bilayers lipid headgroups liquid macromolecules MD simulation membrane minor groove mJ/m² molecular dynamics Molecular dynamics simulation Monte Carlo neutron diffraction nucleic acids nucleotide orientation oxygen phase phosphate groups phosphatidylcholine phospholipid Phys polar polymer polysaccharides potential refinement region relaxation repulsive residues resolution Saenger side-chains solution solvation solvation Gibbs energy solvent solvent molecules solvent structure ẞ-sheet stability Struct studies surface temperature tion water bridges water molecules water structure Westhof X-ray Z-DNA