Water and Biological MacromoleculesWesthof Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging. Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists. |
From inside the book
Results 1-3 of 58
Page 229
... oxygen , the motif most frequently seen , in nucleotides as well as in oligonucleotides , is the ' cone of hydra- tion ' built of three water molecules . This motif was predicted by Pull- man and co - workers using quantum mechanical ...
... oxygen , the motif most frequently seen , in nucleotides as well as in oligonucleotides , is the ' cone of hydra- tion ' built of three water molecules . This motif was predicted by Pull- man and co - workers using quantum mechanical ...
Page 230
... oxygen atoms as well as around the hydroxyl groups of the riboses . There are also three water bridges : one linking C8 ( A ) to an anionic oxygen ; the same anionic oxygen is linked to O5 ' ( C ) via a water molecule ; and the frequent ...
... oxygen atoms as well as around the hydroxyl groups of the riboses . There are also three water bridges : one linking C8 ( A ) to an anionic oxygen ; the same anionic oxygen is linked to O5 ' ( C ) via a water molecule ; and the frequent ...
Page 340
... oxygen atoms on PO ; crystal structure data shown confirm this ( Figure 12.2 ) . Subsequently , the two - bonded oxygen atoms of PO1 be- come hydrated . The total number of water molecules strongly bound to a phosphate group is 7 ± 2 ...
... oxygen atoms on PO ; crystal structure data shown confirm this ( Figure 12.2 ) . Subsequently , the two - bonded oxygen atoms of PO1 be- come hydrated . The total number of water molecules strongly bound to a phosphate group is 7 ± 2 ...
Contents
Water structure | 3 |
Thermodynamic and dynamic properties of water | 45 |
Aqueous solutions of simple hydrophobic solutes | 55 |
Copyright | |
43 other sections not shown
Other editions - View all
Common terms and phrases
Acta Cryst analysis anionic aqueous atoms B-DNA B-form backbone base pairs Beveridge binding Biochemistry Biochim Biol Biomol Biophys Biopolymers calculations Cevc chain Chem Clementi complex conformation counterions crystal structure crystalline crystallographic d(CGCGAATTCGCG density distance dodecamer electron electrostatic Equation experimental Figure force field free energy function Gibbs energy Goodfellow H-bond helix hydration hydration forces hydration shell hydrogen bonds hydrophilic hydrophobic ice Ih interactions interfacial ions lipid bilayers lipid headgroups liquid macromolecules MD simulation membrane minor groove mJ/m˛ molecular dynamics Molecular dynamics simulation Monte Carlo neutron diffraction nucleic acids nucleotide orientation oxygen phase phosphate groups phosphatidylcholine phospholipid Phys polar polymer polysaccharides potential refinement region relaxation repulsive residues resolution Saenger side-chains solution solvation solvation Gibbs energy solvent solvent molecules solvent structure ẞ-sheet stability Struct studies surface temperature tion water bridges water molecules water structure Westhof X-ray Z-DNA