Water and Biological MacromoleculesWesthof Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging. Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists. |
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Page 189
... pairs centred on the helix axis in the manner of B - DNA , but there is considerable base - pair inclina- tion to an extent similar to that seen in AMBER . Also , considerable sequence - dependent fine structure is observed . A second ...
... pairs centred on the helix axis in the manner of B - DNA , but there is considerable base - pair inclina- tion to an extent similar to that seen in AMBER . Also , considerable sequence - dependent fine structure is observed . A second ...
Page 192
... pairs show a consistent inclination in the simulation , in accord with the interpretation of results obtained from ... pairs . Zhurkin theory ( Zhurkin , 1985 ) in base - pair roll is followed in some instances but not in others ...
... pairs show a consistent inclination in the simulation , in accord with the interpretation of results obtained from ... pairs . Zhurkin theory ( Zhurkin , 1985 ) in base - pair roll is followed in some instances but not in others ...
Page 235
... pair , unusual base pairs also present new phosphate- water - base bridges . Thus , in A - A self - pairs the amino N6 of one adenine is linked via a water molecule to an anionic phosphate oxygen of the opposite base ( Figure 7.6 ) . In ...
... pair , unusual base pairs also present new phosphate- water - base bridges . Thus , in A - A self - pairs the amino N6 of one adenine is linked via a water molecule to an anionic phosphate oxygen of the opposite base ( Figure 7.6 ) . In ...
Contents
Water structure | 3 |
Thermodynamic and dynamic properties of water | 45 |
Aqueous solutions of simple hydrophobic solutes | 55 |
Copyright | |
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Acta Cryst analysis anionic aqueous atoms B-DNA B-form backbone base pairs Beveridge binding Biochemistry Biochim Biol Biomol Biophys Biopolymers calculations Cevc chain Chem Clementi complex conformation counterions crystal structure crystalline crystallographic d(CGCGAATTCGCG density distance dodecamer electron electrostatic Equation experimental Figure force field free energy function Gibbs energy Goodfellow H-bond helix hydration hydration forces hydration shell hydrogen bonds hydrophilic hydrophobic ice Ih interactions interfacial ions lipid bilayers lipid headgroups liquid macromolecules MD simulation membrane minor groove mJ/m² molecular dynamics Molecular dynamics simulation Monte Carlo neutron diffraction nucleic acids nucleotide orientation oxygen phase phosphate groups phosphatidylcholine phospholipid Phys polar polymer polysaccharides potential refinement region relaxation repulsive residues resolution Saenger side-chains solution solvation solvation Gibbs energy solvent solvent molecules solvent structure ẞ-sheet stability Struct studies surface temperature tion water bridges water molecules water structure Westhof X-ray Z-DNA