Water and Biological MacromoleculesWesthof Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging. Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists. |
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Results 1-3 of 65
Page 4
... positions and the small spheres denote half - hydrogen ( deuterium ) positions in the disordered model . After Hamilton ( 1968 ) • · tices . The water molecules occupy a wide range of conformational space . Within the known structures ...
... positions and the small spheres denote half - hydrogen ( deuterium ) positions in the disordered model . After Hamilton ( 1968 ) • · tices . The water molecules occupy a wide range of conformational space . Within the known structures ...
Page 32
... positions are projected onto the bc - plane of the unit cell . An acetone molecule is present , separating the two main The solvent regions , which are labelled pocket and channel . The main H - bonded water networks are included as ...
... positions are projected onto the bc - plane of the unit cell . An acetone molecule is present , separating the two main The solvent regions , which are labelled pocket and channel . The main H - bonded water networks are included as ...
Page 259
... positions . Considerable agreement is found with the experimental solvent molecule positions , although there was some evidence that the solvent - solute energies in the simulation using the MCY model of water may be overestimating ...
... positions . Considerable agreement is found with the experimental solvent molecule positions , although there was some evidence that the solvent - solute energies in the simulation using the MCY model of water may be overestimating ...
Contents
Water structure | 3 |
Thermodynamic and dynamic properties of water | 45 |
Aqueous solutions of simple hydrophobic solutes | 55 |
Copyright | |
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Acta Cryst analysis anionic aqueous atoms B-DNA B-form backbone base pairs Beveridge binding Biochemistry Biochim Biol Biomol Biophys Biopolymers calculations Cevc chain Chem Clementi complex conformation counterions crystal structure crystalline crystallographic d(CGCGAATTCGCG density distance dodecamer electron electrostatic Equation experimental Figure force field free energy function Gibbs energy Goodfellow H-bond helix hydration hydration forces hydration shell hydrogen bonds hydrophilic hydrophobic ice Ih interactions interfacial ions lipid bilayers lipid headgroups liquid macromolecules MD simulation membrane minor groove mJ/m² molecular dynamics Molecular dynamics simulation Monte Carlo neutron diffraction nucleic acids nucleotide orientation oxygen phase phosphate groups phosphatidylcholine phospholipid Phys polar polymer polysaccharides potential refinement region relaxation repulsive residues resolution Saenger side-chains solution solvation solvation Gibbs energy solvent solvent molecules solvent structure ẞ-sheet stability Struct studies surface temperature tion water bridges water molecules water structure Westhof X-ray Z-DNA