Water and Biological MacromoleculesWesthof Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging. Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists. |
From inside the book
Results 1-3 of 91
Page 63
... protein folding , during which apolar side - chains tend to be buried in the centre of the protein ( thus reducing their contact with aqueous solvent ) . On folding , intramolecular hydrogen bonds are formed at the expense of protein ...
... protein folding , during which apolar side - chains tend to be buried in the centre of the protein ( thus reducing their contact with aqueous solvent ) . On folding , intramolecular hydrogen bonds are formed at the expense of protein ...
Page 64
... protein - solvent interactions have been studied by many tech- niques , we are going to concentrate on structural aspects of these interac- tions . Thus , the data are ... Protein structures used in analysis of hydration Protein 64 Proteins.
... protein - solvent interactions have been studied by many tech- niques , we are going to concentrate on structural aspects of these interac- tions . Thus , the data are ... Protein structures used in analysis of hydration Protein 64 Proteins.
Page 334
... protein- carbohydrate interactions ' . As a result , ' all the polar groups of the monopyrannoside substrates are involved in hydrogen bonding ' . For the completely buried saccharides described , this means hydrogen bonding to the protein ...
... protein- carbohydrate interactions ' . As a result , ' all the polar groups of the monopyrannoside substrates are involved in hydrogen bonding ' . For the completely buried saccharides described , this means hydrogen bonding to the protein ...
Contents
Water structure | 3 |
Thermodynamic and dynamic properties of water | 45 |
Aqueous solutions of simple hydrophobic solutes | 55 |
Copyright | |
43 other sections not shown
Other editions - View all
Common terms and phrases
Acta Cryst analysis anionic aqueous atoms B-DNA B-form backbone base pairs Beveridge binding Biochemistry Biochim Biol Biomol Biophys Biopolymers calculations Cevc chain Chem Clementi complex conformation counterions crystal structure crystalline crystallographic d(CGCGAATTCGCG density distance dodecamer electron electrostatic Equation experimental Figure force field free energy function Gibbs energy Goodfellow H-bond helix hydration hydration forces hydration shell hydrogen bonds hydrophilic hydrophobic ice Ih interactions interfacial ions lipid bilayers lipid headgroups liquid macromolecules MD simulation membrane minor groove mJ/m² molecular dynamics Molecular dynamics simulation Monte Carlo neutron diffraction nucleic acids nucleotide orientation oxygen phase phosphate groups phosphatidylcholine phospholipid Phys polar polymer polysaccharides potential refinement region relaxation repulsive residues resolution Saenger side-chains solution solvation solvation Gibbs energy solvent solvent molecules solvent structure ẞ-sheet stability Struct studies surface temperature tion water bridges water molecules water structure Westhof X-ray Z-DNA