Water and Biological MacromoleculesWesthof Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging. Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists. |
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Page 238
... residues . Examples of two other types of water bridges already mentioned can also be seen . The resolution of the data is 1.4 A and refinement gave an R - factor of 12.5 % · occurs but is rare ( example in the decamer structure d ...
... residues . Examples of two other types of water bridges already mentioned can also be seen . The resolution of the data is 1.4 A and refinement gave an R - factor of 12.5 % · occurs but is rare ( example in the decamer structure d ...
Page 328
... residue performs numer- ous hydrogen bonds with the lectin residues in site 1 , whereas the two other residues ( Gal and Glc ) are much more exposed to the solvent . One water molecule is linked to Tyr 73 in the unoccupied combining ...
... residue performs numer- ous hydrogen bonds with the lectin residues in site 1 , whereas the two other residues ( Gal and Glc ) are much more exposed to the solvent . One water molecule is linked to Tyr 73 in the unoccupied combining ...
Page 334
... residues within the OCTA molecule itself and between the OCTA molecule and the lectin . A large number of hydration water mol- ecules are also linked to the saccharide . 5 Discussion and Conclusion The examples presented in this study ...
... residues within the OCTA molecule itself and between the OCTA molecule and the lectin . A large number of hydration water mol- ecules are also linked to the saccharide . 5 Discussion and Conclusion The examples presented in this study ...
Contents
Water structure | 3 |
Thermodynamic and dynamic properties of water | 45 |
Aqueous solutions of simple hydrophobic solutes | 55 |
Copyright | |
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Acta Cryst analysis anionic aqueous atoms B-DNA B-form backbone base pairs Beveridge binding Biochemistry Biochim Biol Biomol Biophys Biopolymers calculations Cevc chain Chem Clementi complex conformation counterions crystal structure crystalline crystallographic d(CGCGAATTCGCG density distance dodecamer electron electrostatic Equation experimental Figure force field free energy function Gibbs energy Goodfellow H-bond helix hydration hydration forces hydration shell hydrogen bonds hydrophilic hydrophobic ice Ih interactions interfacial ions lipid bilayers lipid headgroups liquid macromolecules MD simulation membrane minor groove mJ/m² molecular dynamics Molecular dynamics simulation Monte Carlo neutron diffraction nucleic acids nucleotide orientation oxygen phase phosphate groups phosphatidylcholine phospholipid Phys polar polymer polysaccharides potential refinement region relaxation repulsive residues resolution Saenger side-chains solution solvation solvation Gibbs energy solvent solvent molecules solvent structure ẞ-sheet stability Struct studies surface temperature tion water bridges water molecules water structure Westhof X-ray Z-DNA