Water and Biological MacromoleculesWesthof Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging. Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists. |
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Page 32
... shown in Figures 1.17 and 1.18 , respec- tively . The solvent peaks in the 15 K structure appear more ordered than in the 279 K structure . In particular , this can be seen in the channel region . The solvent density at 279 K is mostly ...
... shown in Figures 1.17 and 1.18 , respec- tively . The solvent peaks in the 15 K structure appear more ordered than in the 279 K structure . In particular , this can be seen in the channel region . The solvent density at 279 K is mostly ...
Page 258
... shown hydration sites not only in the minor groove but also in the major groove and along the sugar - phosphate backbone . A number of one- and two - water strand bridges are also seen in this simula- tion . Comparison of simulations of ...
... shown hydration sites not only in the minor groove but also in the major groove and along the sugar - phosphate backbone . A number of one- and two - water strand bridges are also seen in this simula- tion . Comparison of simulations of ...
Page 302
... shown as o . All hydrogen atoms have been omitted and hydrogen bonds are shown as dashed lines . From Yui et al . ( 1992 ) . Reprinted by permission of Elsevier helix - potassium - water - potassium - double helix interactions ( Figure ...
... shown as o . All hydrogen atoms have been omitted and hydrogen bonds are shown as dashed lines . From Yui et al . ( 1992 ) . Reprinted by permission of Elsevier helix - potassium - water - potassium - double helix interactions ( Figure ...
Contents
Water structure | 3 |
Thermodynamic and dynamic properties of water | 45 |
Aqueous solutions of simple hydrophobic solutes | 55 |
Copyright | |
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Acta Cryst analysis anionic aqueous atoms B-DNA B-form backbone base pairs Beveridge binding Biochemistry Biochim Biol Biomol Biophys Biopolymers calculations Cevc chain Chem Clementi complex conformation counterions crystal structure crystalline crystallographic d(CGCGAATTCGCG density distance dodecamer electron electrostatic Equation experimental Figure force field free energy function Gibbs energy Goodfellow H-bond helix hydration hydration forces hydration shell hydrogen bonds hydrophilic hydrophobic ice Ih interactions interfacial ions lipid bilayers lipid headgroups liquid macromolecules MD simulation membrane minor groove mJ/m² molecular dynamics Molecular dynamics simulation Monte Carlo neutron diffraction nucleic acids nucleotide orientation oxygen phase phosphate groups phosphatidylcholine phospholipid Phys polar polymer polysaccharides potential refinement region relaxation repulsive residues resolution Saenger side-chains solution solvation solvation Gibbs energy solvent solvent molecules solvent structure ẞ-sheet stability Struct studies surface temperature tion water bridges water molecules water structure Westhof X-ray Z-DNA