Water and Biological MacromoleculesWesthof Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging. Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists. |
From inside the book
Results 1-3 of 84
Page 108
... solvent molecules , should not exceed unity ( Smith et al . , 1988 ) . For refinement , owing to the high correlation between the B- and Q - factors , damped shifts are applied on alternate cycles ( Hendrickson , 1980 ) . The sites of ...
... solvent molecules , should not exceed unity ( Smith et al . , 1988 ) . For refinement , owing to the high correlation between the B- and Q - factors , damped shifts are applied on alternate cycles ( Hendrickson , 1980 ) . The sites of ...
Page 257
... molecule has also been simulated in the crystal environ- ment using the AMBER molecular dynamics package ( Herzyk et al . , 1991 ) . Simulations with and without restrained solvent molecules showed that although restraining solvent ...
... molecule has also been simulated in the crystal environ- ment using the AMBER molecular dynamics package ( Herzyk et al . , 1991 ) . Simulations with and without restrained solvent molecules showed that although restraining solvent ...
Page 454
... molecule . Here RMR , RM and R , is the locational vector of the i - th nucleus of a . · For each configuration RM one can define the Gibbs energy of the system of one solute a and N solvent molecules . It may be shown that the total ...
... molecule . Here RMR , RM and R , is the locational vector of the i - th nucleus of a . · For each configuration RM one can define the Gibbs energy of the system of one solute a and N solvent molecules . It may be shown that the total ...
Contents
Water structure | 3 |
Thermodynamic and dynamic properties of water | 45 |
Aqueous solutions of simple hydrophobic solutes | 55 |
Copyright | |
43 other sections not shown
Other editions - View all
Common terms and phrases
Acta Cryst analysis anionic aqueous atoms B-DNA B-form backbone base pairs Beveridge binding Biochemistry Biochim Biol Biomol Biophys Biopolymers calculations Cevc chain Chem Clementi complex conformation counterions crystal structure crystalline crystallographic d(CGCGAATTCGCG density distance dodecamer electron electrostatic Equation experimental Figure force field free energy function Gibbs energy Goodfellow H-bond helix hydration hydration forces hydration shell hydrogen bonds hydrophilic hydrophobic ice Ih interactions interfacial ions lipid bilayers lipid headgroups liquid macromolecules MD simulation membrane minor groove mJ/m² molecular dynamics Molecular dynamics simulation Monte Carlo neutron diffraction nucleic acids nucleotide orientation oxygen phase phosphate groups phosphatidylcholine phospholipid Phys polar polymer polysaccharides potential refinement region relaxation repulsive residues resolution Saenger side-chains solution solvation solvation Gibbs energy solvent solvent molecules solvent structure ẞ-sheet stability Struct studies surface temperature tion water bridges water molecules water structure Westhof X-ray Z-DNA