Neurodevelopment and Adult PsychopathologyIn this important 1997 book on the role of neurodevelopmental factors in the pathogenesis of the major psychiatric disorders, the fields of developmental neurobiology, clinical psychiatry and behavioural neuroscience are reviewed by an international group of experts, including many of those responsible for the ideas that have come to dominate current thinking. The first section, 'The Developing Brain', reviews neurodevelopment from the molecular to the behavioural level. Section Two, 'Development and Psychopathology', covers clinical applications of the basic principles of developmental neurobiology. The third and final section, 'Integrative Models', presents approaches toward a synthesis of neurodevelopmental and clinical findings in psychiatric disorder. For students, scientists and clinicians in psychiatry, psychology, and neurodevelopment, this is an essential reference. |
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Contents
Development of the cerebral cortex an overview | 3 |
Development of the primate prefrontal cortex | 12 |
The genetics of neurodevelopment and schizophrenia | 31 |
Glutamate receptors and developmental anomaly in medial temporal lobe in schizophrenia | 57 |
Magnetic resonance imaging studies of developing brain | 63 |
³¹P magnetic resonance spectroscopy studies of developing brain | 71 |
Position emission tomography studies of developing brain | 93 |
Longterm effects of different early rearing experiences on social emotional and physiological development in nonhuman primates | 104 |
Psychopathology and brain dysfunction structural imaging studies | 178 |
Neuropathology neurodevelopment and schizophrenia | 187 |
Neurodevelopmental models of affective disorders | 199 |
Heterogeneity within obsessive compulsive disorder evidence for primary and neurodevelopmental subtypes | 206 |
Schizophrenia a critique from the developmental psychopathology perspective | 213 |
Integrative models | 235 |
Schizophrenia as an emergent disorder of late brain maturation | 237 |
Schizophrenia as a developmental disorder of neural network integrity the dysplastic net hypothesis | 253 |
Other editions - View all
Neurodevelopment and Adult Psychopathology Matcheri S. Keshavan,Robin M. Murray No preview available - 1997 |
Common terms and phrases
abnormalities activity adolescence adult afferents age of onset Arch areas associated autism axons behavioral bipolar bipolar disorder brain development cell cerebral cortex chandelier neurons changes childhood Chugani clinical cognitive controls correlates cortical decrease deficits dendritic disorder dysfunction early effects environmental evidence expression females frontal genes genetic glucose glutamate Goldman-Rakic gray matter Häfner hippocampus human hypothesis imaging impairment increase infants layer lesions levels Lewis magnetic resonance magnetic resonance imaging males membrane mental metabolism migration molecules Murray Nasrallah neural neurodevelopment Neurosci neurotrophins normal NSHD onset of schizophrenia patterns Pettegrew phrenia positron emission tomography postnatal prefrontal cortex premorbid preschizophrenic primate processes proteins Psychiatry Psychol psychopathology psychosis pyramidal neurons Rakic receptors regions rhesus monkeys risk factors samples schizo Schizophr schizophrenia schizophrenic patients sex differences social specific structures studies subplate suggest Suomi symptoms synaptic density synaptic pruning temporal lobe tion visual cortex vivo Weinberger white matter