Handbook of Analytical Therapeutic Drug Monitoring and ToxicologyAdapting modern advances in analytical techniques to daily laboratory practices challenges many toxicologists, clinical laboratories, and pharmaceutical scientists. The Handbook of Analytical Therapeutic Drug Monitoring and Toxicology helps you keep abreast of the innovative changes that can make your laboratory - and the studies undertaken in it - a success. This volume simplifies your search for appropriate techniques, describes recent contributions from leading investigators, and provides valuable evaluations and advice. Discover how to use non-invasively obtained specimens to your best advantage The text features alternative biological specimens such as hair, meconium, saliva, sweat, and vitreous humor, which are not extensively used because they require more sensitive procedures than other biological specimens. How to overcome these limitations is a major topic of the handbook. Experts describe basic principles of innovative techniques and detail how they can be adapted to analyzing alternative biological specimens. The evaluations of the pros and cons of various advances in immunodiagnostics and how they apply to analytes will help you determine their suitability to your own laboratory. The Handbook of Analytical Therapeutic Drug Monitoring and Toxicology helps you make the most of innovative procedures that will open the doors to productive laboratory practices. |
Contents
ANALYTICAL TECHNIQUES | 1 |
Chapter | 13 |
Stereochemical Questions and Some Answers | 21 |
Chapter 3 | 35 |
Chapter 4 | 51 |
Supercritical Fluid Extraction as a Sample Preparation Tool in Analytical Toxicology | 71 |
Chapter 6 | 107 |
Chapter 7 | 127 |
Chapter 11 | 201 |
Chapter 12 | 215 |
Immunoassays and Immunoassay Analyzers for Analytical Toxicology | 223 |
SPECIMENS AND QUALITY ASSURANCE | 237 |
Chapter 15 | 253 |
Chapter 17 | 281 |
Chapter 18 | 303 |
Chapter 19 | 335 |
Other editions - View all
Handbook of Analytical Therapeutic Drug Monitoring and Toxicology (1996) Steven H.Y. Wong,Irving Sunshine No preview available - 2017 |
Common terms and phrases
acid Anal analysis analyte antibody applications assay automated benzoylecgonine binding biological blood buffer calcineurin capillary electrophoresis Chem chemical chiral Chromatogr Clin clinical cocaine compounds concentrations derivatization detection limits detector determination devices digoxin disk DNA testing dose drug monitoring drugs of abuse electrokinetic elution enantiomers enzyme ethanol extraction vessel felbamate Figure fluorescence Forensic Sci GC/MS hair high-performance liquid HPLC human ICP/MS identification immunoassay immunosuppressive injection instrument interface ionization isotope laboratory liquid chromatography mass spectrometry matrix meconium metabolism metabolites method Microcolumn mobile phase modifier morphine ng/ml off-line on-line patients performed phenobarbital plasma polar potential protein pump quadrupole quantitative ratio reagent recoveries reported restrictor saliva sample preparation sensitivity serum solid-phase extraction solubility solvent sorbent SPE column specific specimens spectrum steroids studies supercritical fluid chromatography supercritical fluid extraction tacrolimus techniques temperature tion tissue Toxicol toxicology trace elements trap urine vitreous humor