Topical Antimicrobial Testing and EvaluationProviding industry and academia with the ways of getting products approved by the FDA and the means of servicing expanding markets, this work presents and reviews techniques for testing antibacterial compounds. It discusses and illustrates the most effective methods for testing efficacy and safety of preinjection and preoperative washes, healthcare and food service workers' handwashes, and surgical scrubs. |
Contents
1 General Approach to Developing Topical Antimicrobials | |
2 Skin Properties | |
3 Skin Microbiology | |
4 Current Topical Antimicrobials | |
5 Measurement of Antimicrobial Action of Topical Antimicrobials | |
6 Epistemological Requirements in Evaluating the Effects of Specific Treatments | |
7 Evaluation Strategies and Sample Working Protocols | |
8 Overview of Statistical Methods | |
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Topical Antimicrobial Testing and Evaluation Daryl S Paulson,Taylor & Francis Group No preview available - 2020 |
Common terms and phrases
acids aliquots analysis antimicrobial antimicrobial effectiveness antimicrobial products antimicrobial soap bacteria bacterial cell capsule cell wall chlorhexidine gluconate collected colony count configuration containing cup scrub cytoplasmic membrane decision rule dermis determined difference dilution distribution endospore epidermis error evaluation example experimental food handlers formulation fungi glove juice sampling gluconate Gram-negative Gram-positive hands handsoaps healthcare personnel handwash hyphae investigator iodine iodophors juice sampling procedure keratinization laboratory layer level of significance logi0 Mann-Whitney manufacturers measurement methods microbial populations microorganisms neutralizers nonparametric normal microbial flora null hypothesis number of viable outer membrane parameter parametric statistics PCMX peptidoglycan performed plate counts polysaccharides preoperative prepped proteins R-value ranks region reject H0 requirements residual skin skin-prepping Soybean-casein species Step sterile structure Student’s subjects surface surgical scrub teichoic acids test product test statistic tion tissue topical antimicrobial treatment type I error utilized validity variable variance viruses