Multi-Drug Resistance in Emerging and Re-Emerging Diseases

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R. C. Mahajan, Amu Therwath
CRC Press, 2001 - Medical - 282 pages
The recent appearance of multi-drug resistant phenotypes has complicated the efforts to completely eradicate diseases such as tuberculosis and malaria, thus underscoring the need for new and innovative scientific approach to the problem. Multi-Drug Resistance in Emerging and Re-Emerging Diseases highlights the state-of-the-art in microbial/parasite control and containment, and discusses ways and means of avoiding development of drug resistance. It explores strategies to combat the nightmare of microbial aggression and resistance and to overcome multiple drug resistance when it emerges in microbial organisms or in cancer cells exposed to chemotherapy.

Written by a panel of experts, the book gives you the benefits of both field and clinical experience as well as an in-depth know-how of the pathology of these drug resistant diseases. Topics include malaria, tuberculosis, cholera, leprosy, diarrhoeal diseases, nosocomial diseases, plague, and drug resistance and cancer. Multi-Drug Resistance in Emerging and Re-Emerging Diseases provides a foundation for new initiatives and more collaborative efforts in the fight against resistance to antibiotics by micro-organisms.
 

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Contents

Drug Resistance in Cancer
1
Its Impact on Treatment of Aids and TB
15
Current Pandemics of Cholera and Strategy
23
Emerging Clones of Vibrio Cholerac and Multi
31
Emergence of PlasmidMediated Antibiotic Resistance
43
Progress and Prospect of Chemotherapy Research
49
Diagnosis of Leprosy in IndiaRelevance
65
New Drug Targets in Tuberculosis
75
New Targets for Malaria Drug Development
147
Molecular Aspects of Chloroquine and Antifols
157
Import of Host Enzymes into the Malarial Parasite
169
New Drugs Against Malaria with Special Reference
175
Status of Drug Resistance in Malaria in India
191
Can India Control the Spread of HIVAIDS?
211
A Strategy to control the Emergence
219
Opportunistic Fungal and Mycobacterial Infections
235

Newer DNA Fingerprinting Techniques
87
The Molecular Basis of Isoniazid Resistance
97
Studies on Gene
109
Progress for Deciphering Mycobacterium
125
MultiDrug Resistant Tuberculosis
133
Pathogenicity of Enterovirulent Escherichia coli
243
P53 BCL2 and Drug Resistance in Cancer
249
Diagnostic Tools in Clinical for MDR
259
Multiple Drug Resistance in Solid Tumors
271
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