Pathophysiology of Lipid Peroxides and Related Free RadicalsKunio Yagi This book is an edited version of the contributions to an international symposium commemorating the 20th anniversary of the Japanese Society of Lipid Peroxide and Free Radical Research held in Inuyama City, Japan. The papers are presented in mini-review style, so that the volume has assumed the form of an advanced guidebook for specialists. The pathophysiology of lipid peroxides and related free radicals is now recognized to be one of the most important issues in the pathogenesis of many diseases. This volume covers diverse topics such as retinal pathology, digestive diseases, antioxidant defence and cancer chemotherapy, as well as more abstract topics related to lipid peroxides and free radicals. The papers collected in this book will contribute much to the improvement of medical sciences, especially to that of clinical medicine, the main goal of which is human welfare. |
Contents
Preface | 1 |
Detection of Oxidized Phosphatidylcholines in Human Athero | 13 |
Interaction of Superoxide Nitric Oxide and Peroxynitrite under | 25 |
Copyright | |
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Common terms and phrases
12-lipoxygenase 9-CHO PC a-tocopherol airway antibody antioxidant antioxidative activity apoB apoptosis arachidonic acid assay Biochem Biol Biophys buffer Ca2+ Cancer cells Chem cholesterol concentration curcumin cyt P-450 reductase cytotoxic DEP group DLH3 DT-diaphorase enzyme Ernster Free Rad Free Radicals gastric mucosa gene GPX activity GSH-Px H₂O₂ HPLC human hydroperoxides inactivation increase incubated induced inhibited injury ischemia-reperfusion Japan Sci LDL oxidation levels leukocyte lipid hydroperoxides lipid peroxidation lipoproteins lipoxygenases mechanism membrane menadione molecule mutant myocytes NADH neutrophils NO₂HPA O₂ OH OH ONOO oxidation of LDL oxidative stress OxLDL OxPC oxygen P187S mutation Pathophysiology of Lipid PCOOH peak Peroxides and Related Pharmacol PHGPx plasma platelet porcine leukocyte probucol protein quinone reductase reaction reactivity redox reduced reductase activity Related Free Radicals retinal role sesaminol showed significantly substrate superoxide dismutase tion tissue Tokyo/S transfectant troglitazone ubiquinol vitamin vitamin K wild-type Zn-SOD