Science of Synthesis: Biocatalysis in Organic Synthesis, Volume 1
Georg Thieme Verlag, Mar 11, 2015 - Science - 648 pages
The three Science of Synthesis volumes on "Biocatalysis in Organic Synthesis" are designed to present the new possibilities offered by modern biocatalysis to the nonspecialist academic and industrial readership who are involved in practical organic synthesis. The goal of the reference work is to help start a new wave of enthusiasm for biocatalysis in the broader community and to give an overview of the field. As is the case with all of the Science of Synthesis volumes, "Biocatalysis in Organic Synthesis" offers critical reviews of organic transformations by experts, including typical or general experimental procedures. The content organization of the three volumes is based on the type of reaction performed under biocatalysis. Volume 1 begins with chapters discussing the historical development of the field, sources of enzymes and appropriate selection of catalysts, and general strategies employed in biocatalysis. This is followed by reviews of the biocatalytic hydrolysis of various substrates. The volume concludes with chapters devoted to biocatalytic isomerizations, and the synthesis of glycosides.
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Biocatalysis in Organic Synthesis 1 Reference Library 20145 11 Introduction
Biocatalysis in Organic Synthesis 1 Reference Library 20145 12 Strategies and Methods in Biocatalysis
Biocatalysis in Organic Synthesis 1 Reference Library 20145 13 Hydrolysis and Transacylation Esterases Lipases Phosphatases and Phosphoryl Tran...
Biocatalysis in Organic Synthesis 1 Reference Library 20145 14 Nitrile and Amide Hydrolysis and Enzymatic Synthesis of Amides and Peptides
Biocatalysis in Organic Synthesis 1 Reference Library 20145 15 Isomerizations Racemization Epimerization and EZIsomerization
Biocatalysis in Organic Synthesis 1 Reference Library 20145 16 Glycosides
Biocatalysis in Organic Synthesis 1 Reference Library 20145 Keyword Index
Biocatalysis in Organic Synthesis 1 Reference Library 20145 Abbreviations
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1-phosphate acetate activity acyl acyl donor acylase alcohol aldolase amidase amide amines amino acid aminolysis Asymmetry Biocatalytic Retrosynthesis Biochem Biol Biotechnol Biotransformations buffer pH CALB Candida Candida antarctica carbohydrates carboxylic acids Catal catalysts catalyzed Chem chemical chemoenzymatic chiral CO2H coli compounds concentration conversion d-amino dehydrogenase desymmetrization dynamic kinetic resolution enantiomer enantiomeric excess enantiopure enantioselective enzymatic hydrolysis enzyme esterase esters formation glycerol HPLC hydantoin hydantoinase hydrolases hydrolysis hydrolysis of racemic hydrolyze immobilized intermediate isomerase ketone kinase kinetic resolution l-N-carbamoylase lipase catalyzed lyzed methyl microbial Microbiol mixture mmol nitrilase nitrile hydratase OH OH OH penicillin phosphatase phosphate buffer phosphorylation porcine prochiral protein Pseudomonas putida pyruvate R1 OH racemase racemic reaction recombinant resolution of racemic Rhodococcus sp Scheme soln solvent stereoselective substrate scope sucrose Synth synthetic tion whole-cell yield zymes