Acute Phase Proteins Molecular Biology, Biochemistry, and Clinical ApplicationsAcute Phase Proteins covers all major aspects of acute phase proteins (APP) starting with molecular mechanisms regulating their synthesis and ending with their functional significance. The book features 36 chapters addressing such topics as acute phase response and the APP; major APP and their structure and functions; regulation of APP synthesis, the cytokines and hormones implicated in these processes, and molecular mechanisms involved; signal transduction of cytokines in hepatocytes and posttranscriptional processes; and quantitative and qualitative evaluation of APP in clinical practice. The book will be an important reference for immunologists, molecular biologists, cellular biologists, biochemists, and clinical chemists. |
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Page 6
... activity , as recently reveiwed by Volanakis . 10 His review serves as the basis for portions of this section . These categories , however , do not include all of the APP , since biological functions of some others , notably SAA , are ...
... activity , as recently reveiwed by Volanakis . 10 His review serves as the basis for portions of this section . These categories , however , do not include all of the APP , since biological functions of some others , notably SAA , are ...
Page 7
... activity , 18 and modulation of phagocytic cell function . In addition , CRP apparently is able to inhibit platelet - activating factor . 19 Mannan - binding protein ( MBP ) is an acute phase lectin with specificity for terminal ...
... activity , 18 and modulation of phagocytic cell function . In addition , CRP apparently is able to inhibit platelet - activating factor . 19 Mannan - binding protein ( MBP ) is an acute phase lectin with specificity for terminal ...
Page 12
... activity inhibitory to platelet aggregation97 or with loss of the ability to inhibit mitogen - induced lymphocyte ... activity by monocytes 100 than are the Con A - reactive forms . The Con A - nonreactive form of PI is more effective in ...
... activity inhibitory to platelet aggregation97 or with loss of the ability to inhibit mitogen - induced lymphocyte ... activity by monocytes 100 than are the Con A - reactive forms . The Con A - nonreactive form of PI is more effective in ...
Page 13
... activity , accompanied by an increase of tri- and tetraantenary glycans on glycoproteins . It should be noted that reduced GnT III activity might also contribute to formation of more branched structures , since GnT III and GnTV compete ...
... activity , accompanied by an increase of tri- and tetraantenary glycans on glycoproteins . It should be noted that reduced GnT III activity might also contribute to formation of more branched structures , since GnT III and GnTV compete ...
Page 26
... activity decreased dramatically immediately after induction of inflammation . The early decrease in transcriptional activity preceded the reduction in mRNA levels . About 24 h after induction of inflammation , the transcriptional activities ...
... activity decreased dramatically immediately after induction of inflammation . The early decrease in transcriptional activity preceded the reduction in mRNA levels . About 24 h after induction of inflammation , the transcriptional activities ...
Contents
Chapter 18 | 321 |
Chapter 19 | 329 |
Chapter 20 | 343 |
Regulation of CReactive Protein Haptoglobin and Hemopexin Gene | 365 |
Chapter 22 | 397 |
Chapter 24 | 412 |
Transcriptional Regulation of the Human C3 Gene | 425 |
Chapter 25 | 443 |
Chapter 6 | 107 |
Chapter 7 | 117 |
Chapter 8 | 149 |
Chapter 9 | 169 |
Chapter 10 | 185 |
Chapter 11 | 207 |
Chapter 12 | 223 |
Chapter 13 | 239 |
Chapter 14 | 255 |
Chapter 15 | 275 |
Chapter 16 | 289 |
Chapter 17 | 309 |
Chapter 26 | 467 |
Chapter 27 | 495 |
Chapter 28 | 511 |
Chapter 29 | 529 |
Chapter 30 | 547 |
Chapter 31 | 559 |
Chapter 32 | 581 |
Chapter 33 | 603 |
Chapter 35 | 633 |
Glycoforms of aAcid Glycoprotein as Disease Markers | 651 |
INDEX | 665 |
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Common terms and phrases
a₂-M Acad activity acute phase proteins acute phase response addition albumin amino acid analysis Baumann binding Biochem Biol biological blood C-reactive protein C/EBP cDNA cell lines changes Chem complement complex concentration containing culture cytokines determined domain effect elements expression factor fibrinogen Figure function gene gene expression glucocorticoids glycoprotein glycosylation growth haptoglobin Hep G2 hepatic hepatocytes hepatoma cells human identified Immunol increase indicated induced inflammation inhibition inhibitor injection interaction interleukin-6 involved isolated levels liver major mechanism mediated mice molecular molecule mouse mRNA murine necrosis normal nuclear observed peptide plasma proteins present primary Proc production promoter proteinase inhibitors receptor References region regulation reported residues role Schreiber secretion sequence serpins serum serum amyloid showed shown signal similar specific stimulation structure studies suggested synthesis thiostatin tissue transcription transthyretin tumor vitro vivo