Water and Biological Macromolecules

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CRC Press, Aug 16, 1993 - Science - 468 pages
Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging.

Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists.

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Contents

Water structure
4
Results
41
Thermodynamic and dynamic properties of water
45
Hydration of amino acids in protein crystals
83
Discussion
90
Highresolution
98
Other methods
129
Perspectives
135
11
313
The role of structural water molecules in proteinsaccharide
321
129
333
Lipid hydration
338
19
368
21
379
149
381
39
387

Hydration of protein secondary structures the role
148
6
165
Structural water bridges in nucleic acids
226
Hydration sites and hydration bridges around DNA helices
253
98
261
Light scattering spectroscopy studies of the water molecules
266
1
288
101
301
Polysaccharide interactions with water
303
Hydration forces
393
lvation thermodynamics of biopolymers
430
45
443
48
452
338
460
154
461
268
464
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Page 381 - Interacting phospholipid bilayers: measured forces and induced structural changes.

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