Evolution of Infectious Disease
Findings from the field of evolutionary biology are yielding dramatic insights for health scientists, especially those involved in the fight against infectious diseases. This book is the first in-depth presentation of these insights. In detailing why the pathogens that cause malaria, smallpox, tuberculosis, and AIDS have their special kinds of deadliness, the book shows how efforts to control virtually all diseases would benefit from a more thorough application of evolutionary principles. When viewed from a Darwinian perspective, a pathogen is not simply a disease-causing agent, it is a self-replicating organism driven by evolutionary pressures to pass on as many copies of itself as possible. In this context, so-called "cultural vectors"--those aspects of human behavior and the human environment that allow spread of disease from immobilized people--become more important than ever. Interventions to control diseases don't simply hinder their spread but can cause pathogens and the diseases they engender to evolve into more benign forms. In fact, the union of health science with evolutionary biology offers an entirely new dimension to policy making, as the possibility of determining the future course of many diseases becomes a reality. By presenting the first detailed explanation of an evolutionary perspective on infectious disease, the author has achieved a genuine milestone in the synthesis of health science, epidemiology, and evolutionary biology. Written in a clear, accessible style, it is intended for a wide readership among professionals in these fields and general readers interested in science and health.
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LibraryThing ReviewUser Review - jamclash - LibraryThing
Vector evolution is fascinating...if you let it. To think that certain bacteria, as Ewald claims, have evolved to modify the behavior of their hosts to perpetuate their own kind is astounding to me ... Read full review
Vectors Vertical Transmission and the Evolution of Virulence
How to Be Severe Without Vectors
When Water Moves like a Mosquito
AttendantBorne Transmission Or How Are Doctors and Nurses like Mosquitoes Machetes and Moving Water?
War and Virulence
Where Did It Come from and Where Is It Going?
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Acad Acquired Immune Defic Africa antibiotic resistance antibodies areas associated asymptomatic attendantborne transmission bacteria benefit benign Blattner blood Cancer cause cultural vectors hypothesis cycle death defense diarrhea diarrheal diseases diphtheria effects el tor epidemic epidemiology evolution evolutionary evolve Ewald example falciparum favor fever gene genetic HIV infection HIV’s homosexuals hospital hospitalacquired host HTLV HTLVI human immunodeficiency virus immune system immunodeficiency virus type increased virulence individuals infected cells infectious diseases influenza isolated Kaposi’s sarcoma Lancet lethal longterm malaria monkeys mosquito mutations needleborne numbers occur onset organisms outbreaks pandemic parasites pathogens Plasmodium Plasmodium falciparum population potential prevalence progression to AIDS protein reduced relatively replication rate reproduction response reverse transcriptase Reye’s syndrome severe sexual contact sexual partner rates Shigella species spread strains studies susceptibles symptoms Syndr therapy tissues transmitted treatment tuberculosis vaccine variation vectorborne Vibrio cholerae viral Virol viruses waterborne transmission zidovudine