Biology, Pages 82-91 |
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Page 69
Figure 5.20 Exploring Levels of Protein Structure 84 Sickle - Cell Disease : A
Simple Change in Primary Structure Even a slight change in primary structure
can affect a protein's conformation and ability to function . For instance , the
substitution ...
Figure 5.20 Exploring Levels of Protein Structure 84 Sickle - Cell Disease : A
Simple Change in Primary Structure Even a slight change in primary structure
can affect a protein's conformation and ability to function . For instance , the
substitution ...
Page 70
disorder . Normal red blood cells are disk - shaped , but in sickle - cell disease ,
the abnormal hemoglobin molecules tend to crystallize , deforming some of the
cells into a sickle shape ( Figure 5.21 ) . The life of someone with the disease is ...
disorder . Normal red blood cells are disk - shaped , but in sickle - cell disease ,
the abnormal hemoglobin molecules tend to crystallize , deforming some of the
cells into a sickle shape ( Figure 5.21 ) . The life of someone with the disease is ...
Page 71
Figure 5.21 A single amino acid substitution in a protein causes sickle - cell
disease . To show fiber formation clearly , the orientation of the hemoglobin
molecule here is different from that in Figure 5.20 . What Determines Protein
Conformation ...
Figure 5.21 A single amino acid substitution in a protein causes sickle - cell
disease . To show fiber formation clearly , the orientation of the hemoglobin
molecule here is different from that in Figure 5.20 . What Determines Protein
Conformation ...
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Activity amino acid sequence answers arrangement atoms bind Biology blood bonds break build built called Carbohydrates carbon cell chaperonin chemical Chemistry complementary complex components compounds Concept conformation connected consists correct cytoplasm cytosine denatured denatured protein deoxyribose sugars determines differ directions DNA and Proteins DNA double helix DNA molecule Emergent endorphins environment enzyme evolutionary fats fatty acids Figure flow folding four function genes genetic information glucose glycosidic linkages hemoglobin humans hydrogen bonds interactions joined known linked macromolecules molecular monomers mRNA nitrogenous bases normal nucleic acids nucleotides organic pairs particular pentose phosphate group polymers polynucleotide polynucleotide strand polypeptide chain primary structure production properties Protein Structure purines pyrimidine result ribosomes ring secondary separated sequence of bases serve shape share shown sickle-cell disease similar specific starch Steroids strand sugar sugar-phosphate backbone synthesis three-dimensional types unique