Reproductive Toxicology: In Vitro Germ Cell Developmental Toxicology, from Science to Social and Industrial Demand

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Jesús del Mazo
Springer Science & Business Media, Jun 29, 2013 - Medical - 223 pages
Numerous reports demonstrate that the reproductive system could be affected by multiple potential toxicological agents. The volume includes different aspects of the development of new approaches to in vitro testing using sperm cells and systems involved on reproduction in mammals. Comparative analysis of in vivo and in vitro methods has been included to take steps towards the further development of and applications of new systems for germline toxicology.
 

Contents

1 ADVANCES IN IMPROVING HUMAN RISK ESTIMATION
1
Assays to measure estrogen and androgen agonists and antagonists Ana M Soto
9
Development of a marker of estrogenic exposure in breast cancer patients Patricia
29
primordial germ cells
41
Cell culture systems for the analysis of the male germinal differentiation Minoo
51
In vitro survival of human neoplastic germ cells Ewa RajpertDe Meyts Heidrun
59
Effects of rapamycin and fk 506 on rat sertoli cells in vitro Nicole Clemann and
67
published reports see references He considered more appropriate to include here a summary of his oral
76
In vitro analysis of xenoestrogens by enzyme linked receptor assays ELRA Martin
113
suggestions for a greater role in developmental
129
Molecular cloning and developmental pattern of expression of msj1 a new male
145
Biochemical characterization of benomyl inhibition on endometrial growth during
163
A new assay to assess aneuploidy in humanhamster embryos Immaculada Ponsa
185
Single day treatment
191
The effect of parathion on mouse testicular and epididymal development cultured
201
Evaluation of xenoestrogenic effects in fish on different organization levels Betting
207

DNA damage in human and mouse spermatozoa after in vitroirradiation assessed
79
In vitro models for the investigation of reproductive toxicology in the testis Brian A
95
Effects on female fertility and germinal cells in prepubertal and adult rats Rattus
215
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