Inflammatory Bowel DiseaseRichard P. MacDermott, William F. Stenson |
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Page 58
... antigen to immunocompetent T cells . The difference relates to the type of T cell activated . In the rat and human , epithelial cells stimulate the proliferation of CD8 + cells ( antigen specific and nonspecific in rat , 32 antigen ...
... antigen to immunocompetent T cells . The difference relates to the type of T cell activated . In the rat and human , epithelial cells stimulate the proliferation of CD8 + cells ( antigen specific and nonspecific in rat , 32 antigen ...
Page 61
... antigen presentation and the effects of T - cell activation on humoral immunity systemically and within GALT . Antigen Presentation As discussed earlier , there are three major antigen - presenting cells in GALT : the tissue macrophage ...
... antigen presentation and the effects of T - cell activation on humoral immunity systemically and within GALT . Antigen Presentation As discussed earlier , there are three major antigen - presenting cells in GALT : the tissue macrophage ...
Page 62
... antigen processing combined with enhanced class II antigen expres- sion may result in increased T - cell activation ( predominantly CD4 + T cells ) and an immunologic cascade of chronic inflammation . As the mucosal barrier is altered ...
... antigen processing combined with enhanced class II antigen expres- sion may result in increased T - cell activation ( predominantly CD4 + T cells ) and an immunologic cascade of chronic inflammation . As the mucosal barrier is altered ...
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abnormalities acid action activity addition agents alterations antibodies antigens appear associated bacterial blood cause chronic Clin clinical colonic compared complement complex component Crohn's disease cytokines cytotoxic decreased defect determined diarrhea effects enhanced epithelial cells epithelium et al evidence expression factor findings function Gastroenterology genes genetic granulomas growth human immune immune response Immunol immunologic important incidence increased induced infection inflammation inflammatory bowel disease inhibition initially injury intestinal involved isolated lamina propria lesions leukocyte levels lymphocytes macrophages markers mast cells mechanisms mediators mononuclear mucin mucosal Nature neutrophils normal observed occur patients population possible potential present production prostaglandin protein rates recent receptor regulation relatives release reported response risk role schistosomiasis secretion secretory serum shown specific stimulation studies suggest T-cell tissue ulcerative colitis vitro