Inflammatory Bowel DiseaseRichard P. MacDermott, William F. Stenson |
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Page 79
... mucosa and peripheral blood also differ ; T cells expressing the CD45RO surface marker represent memory T cells and are predominant in the mucosa , whereas the subset expressing the CD45RA isoform are naive cells and predominate in the ...
... mucosa and peripheral blood also differ ; T cells expressing the CD45RO surface marker represent memory T cells and are predominant in the mucosa , whereas the subset expressing the CD45RA isoform are naive cells and predominate in the ...
Page 81
... mucosa . Mitogen - induced cel- lular cytotoxicity has been used as an indirect measure of T - cell cytotoxic- ity , 26,40,41 and has been reported to be decreased in the mucosa and blood of patients with IBD41 ; however , the ...
... mucosa . Mitogen - induced cel- lular cytotoxicity has been used as an indirect measure of T - cell cytotoxic- ity , 26,40,41 and has been reported to be decreased in the mucosa and blood of patients with IBD41 ; however , the ...
Page 109
... mucosa colitis , mucosa with lost glands with lost glands ( n = 7 ) IgG 63 % ( x220 ) 830 IC / unit IgG 77 % ( x125 ) ( x18 ) ( n = 4 ) 945 IC / unit ( x6.6 ) 200 400 A 600 800 1000 1200 Height of mucosal tissue unit ( μm ) 200 400 600 ...
... mucosa colitis , mucosa with lost glands with lost glands ( n = 7 ) IgG 63 % ( x220 ) 830 IC / unit IgG 77 % ( x125 ) ( x18 ) ( n = 4 ) 945 IC / unit ( x6.6 ) 200 400 A 600 800 1000 1200 Height of mucosal tissue unit ( μm ) 200 400 600 ...
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abnormalities acid action activity addition agents alterations antibodies antigens appear associated bacterial blood cause chronic Clin clinical colonic compared complement complex component Crohn's disease cytokines cytotoxic decreased defect determined diarrhea effects enhanced epithelial cells epithelium et al evidence expression factor findings function Gastroenterology genes genetic granulomas growth human immune immune response Immunol immunologic important incidence increased induced infection inflammation inflammatory bowel disease inhibition initially injury intestinal involved isolated lamina propria lesions leukocyte levels lymphocytes macrophages markers mast cells mechanisms mediators mononuclear mucin mucosal Nature neutrophils normal observed occur patients population possible potential present production prostaglandin protein rates recent receptor regulation relatives release reported response risk role schistosomiasis secretion secretory serum shown specific stimulation studies suggest T-cell tissue ulcerative colitis vitro