Risk and Protective Factors in Schizophrenia: Towards a Conceptual Model of the Disease ProcessHeinz Häfner H. HAFNER Schizophrenia Research Unit, Central Institute of Mental Health, Mannheim, Germany The present volume contains the lectures and invited discussions of the sympo sium on "Risk and protective factors in schizophrenia - towards a conceptual model of the disease process", which was held at the International Science Forum of the University of Heidelberg from October 25 to 27, 200l. They are supple mented by a "Summary and outlook", in which Peter Jones gives a brief overview of the results and perspectives featured in the presentations and discussions. The contributions and discussions reflect the open-minded and creative atmosphere at the meeting. The systematically structured program of the symposium continued the tradition of the Search for the Causes of Schizophrenia symposia, which were th started in 1986 on the occasion of the 600 anniversary of the University of Hei delberg and which are co-organized with Prof. Wagner Farid Gattaz/Sao Paulo. The aim of these symposia and their proceedings volumes [6,8-10] has been to reflect the state of the art in schizophrenia research at their time, and they have successfully done so. In contrast, the present symposium pursued a more lim ited objective and was of a different type. It brought together, around a large table at the International Science Forum in Heidelberg, 22 invited speakers and dis cussants and an equal number of young scientists working in the research fields in question, who were thus given an opportunity to listen and to participate. |
Contents
Genetics of schizophrenia and related disorders | 3 |
Genotypeenvironment interaction in the Finnish adoptive family study Interplay between genes and environment? | 23 |
psychological and social risk mechanisms for psychosis | 33 |
Developmental Disorders of the Brain | 53 |
is there evidence for a neurodevelopmental disorder? | 55 |
Highrisk studies and neurodevelopmental hypothesis | 65 |
Are structural cerebral changes progressive in schizophrenia? | 77 |
developmental disorders of the brain | 93 |
Psychopathological Predictors of Onset and Course of Schizophrenia | 185 |
Predicting the onset of schizophrenia | 187 |
The early course of schizophrenia | 201 |
Testing models of the early course of schizophrenia | 223 |
psychopathological predictors of onset and course of schizophrenia | 237 |
Perspectives of Neuroprotective Interventions | 249 |
Neuroprotection in schizophrenia What does it mean? What means do we have? | 251 |
mechanisms of action | 257 |
Environmental Risk Factors | 97 |
Obstetric complications maternal psychopathology and the risk of psychosis | 99 |
Migration and the social epidemiology of schizophrenia | 107 |
Urbanrural life as a risk factor? | 117 |
Environmental risk factors of psychosis | 127 |
Indicators of Schizophrenia in Childhood and Adolescence | 133 |
Risk factors for schizophrenia in childhood and youth | 135 |
Association between cognitive and behavioral functioning nonpsychotic psychiatric diagnoses and drug abuse in adolescence with later hospitalizatio... | 157 |
Specificity of basic symptoms in early onset schizophrenia | 171 |
indicators of schizophrenia in childhood and adolescence | 179 |
avenue to neuroprotection in schizophrenia | 265 |
Psychoprotective Factors | 277 |
empirical evidence of efficacy and open questions | 279 |
Cognitivebehavior therapy in the treatment of schizophrenia | 289 |
Coping and social support as protective factors | 297 |
Protective interventions in schizophrenia | 315 |
319 | |
Risk and protective factors in schizophrenia Towards a conceptual model of the disease process | 321 |
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Risk and Protective Factors in Schizophrenia: Towards a Conceptual Model of ... Heinz Häfner No preview available - 2002 |
Common terms and phrases
abnormal admission adolescents adult antioxidant antipsychotic Arch Gen Psychiatry assessment association basic symptoms behavior Biol Psychiatry birth cohort brain changes childhood chronic clinical cognitive controls coping coping reactions correlation course of schizophrenia delusions depression depressive mood develop schizophrenia developmental diagnosis disease drug abuse duration early course effect environmental episode estradiol estrogen estrogen receptor family intervention first-episode follow-up frontal frontal lobe functioning genes genetic Häfner H hallucinations illness onset increased individuals interaction IRAOS Jones PB linkage lobe maternal mental minus symptoms Murray RM negative symptoms neurodevelopmental neuronal neuroprotective Obstetric complications outcome PANSS personality phrenia population positive symptoms postnatal depression predictive predictors prevalence Psychiatry psychopathology psychosis psychotic disorder psychotic symptoms receptor relapse relatives risk factors risk for schizophrenia sample schizo Schizophr Bull Schizophr Res schizophrenic patients schizotypy scores significant studies Tarrier temporal lobe therapy thought disorders tion treatment variables volume vulnerability