Advanced Therapy of Inflammatory Bowel Disease: Ulcerative ColitisNow published in two volumes to accommodate new chapters on the many advances in understanding and treatment options, this set of volumes represents the definitive reference on inflammatory bowel disease, a spectrum of diseases that is receiving increasing attention as our understanding of the etiological factors increases and diagnostic tools are refined. Basic research accelerated at the beginning of this decade and is now yielding new, more targeted treatments than were available just a few years ago. Volume 1 is on IBD and Ulcerative Colitis, and Volume 2 is on IBD and Crohn's Disease. All areas that were covered in the 2nd edition have been expanded and updated. New sections include the rapidly expanding knowledge of genetics and the role of the intestinal flora and environmental factors in etiology and pathogenesis. Among the 168 chapters, there are 20 on biologic therapies and 30 on surgical management. The consultant/authors clearly state their approach to important issues, such as the duration of immunomodulator and of anti-TNF-a use and the options for managing isolated low-grade dysplasia. A strong focus on the individual patient is woven throughout both volumes, including the benefits and risks of potentially life-altering therapies and surgeries. Entire sections detail concerns about the well-being of each person. This book provides information for health professionals who help both pediatric and adult patients navigate through the lifelong shadow of a chronic, probably genetically determined ordeal. |
Contents
3 | |
18 | |
Moffatt and Charles N Bernstein Clinical Relevance | 69 |
Expectations for the Patient with Steven R Brant | 75 |
Living with Ulcerative Colitis 21 Clifton Huang and Subra Kugathasan | 81 |
Living with Crohns Disease 25 Justina J Sam and Geoffrey C Nguyen | 87 |
Interactions among the Charles Wang and Lloyd Mayer | 95 |
Recognizing and Managing | 109 |
Genetic Testing for IBD 317 | 411 |
ULCERATIVE COLITIS 67 IBD of Undetermined Type | 417 |
DietaryInduced Symptoms in Patients with Ulcerative Colitis | 423 |
Sequential and Combination Therapy of Myles R Joyce and Victor W Fazio | 433 |
Predicting Relapses | 439 |
Aminosalicylate Therapy | 445 |
Steroid Unresponsiveness in IBD 371 Evaluating Chronic Pouches | 453 |
Methotrexate Use in Chronic Ulcerative Colitis | 465 |
Jacques Cosnes and Philippe Seksik | 117 |
Clinical Measures of Disease Activity 125 Yvette Leung and Lloyd R Sutherland | 213 |
The Role of Genetics and Serology in 36 Viral Infections in IBD | 221 |
History of IBD 135 | 231 |
Presentations | 239 |
Clinical Utility of Quality of 39 Smoking and Crohns Disease | 245 |
Magnifying Colonoscopy in Syndrome and IBD | 257 |
Horton and Elliot K Fishman Pregnancy on IBD | 267 |
Imaging IBD with FDG Raja Affendi Raja Ali and Laurence J Egan | 273 |
PET and PETCT 189 | 279 |
Transabdominal Bowel Sonography in Management of IBD | 287 |
What 63 Management of Severe Colitis 395 | 307 |
AntiTNF Agent Use in Advances and Complications | 473 |
Gearhart Prevention and Treatment | 549 |
Waqqas Afif and Edward V Loftus | 555 |
Lymphoma Risks in IBD 489 92 Sclerosing Cholangitis | 563 |
Enhanced Visualization Techniques for Cholangiocarcinoma in Primary | 569 |
Extraintestinal Manifestations of IBD 519 Paul Angulo and Willem J S de Villiers | 577 |
Management of Skin Disorders in Problems and Thrombosis in IBD | 583 |
Ocular Manifestations of IBD 533 Robert J Bonasera and James H Grendell | 589 |
Arthritis and IBD 537 Karen I Kroeker and Richard N Fedorak | 596 |
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Common terms and phrases
abdominal adalimumab adolescents adults agents anastomosis anti-TNF antibody assess associated azathioprine biological biopsies cancer cells chronic Clin Gastroenterol Hepatol clinical Clostridium difficile cohort colectomy colon colonoscopy colorectal complications corticosteroids Crohn's disease cyclosporine cytokines diagnosis diarrhea disease activity dose drug dysplasia Editor's note TMB efficacy endoscopic enemas evaluation fistula follow-up function Gastroenterology genes genetic IBD patients ileal ileostomy immune immunomodulators immunosuppressive induce infection Inflamm Bowel inflammation inflammatory bowel disease infliximab initial intestinal IPAA lesions long-term maintenance markers mesalamine mucosal mutations natalizumab NOD2 NSAIDs onset oral outcomes patients with Crohn's patients with IBD pediatric perianal physician placebo population-based pouch pouchitis probiotics randomized rectal refractory relapse remission reported response risk factors role Sandborn WJ severe side effects small bowel smoking steroids stoma strictures surgery surgical symptoms syndrome testing therapeutic tion treated treatment trial UC patients ulcerative colitis variants weeks