Mouse Development: Patterning, Morphogenesis, and OrganogenesisThis book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference. *Broad-based overview of mouse development from fundamental to specialist levels*Extensive coverage of a wide range of developmental mutations of the mouse*Excellent benchmark illustrations of brain, craniofacial, gut and heart development*In-depth experiment-based assessment of concepts in mammalian development*Focus on models of specific relevance to human development*Comprehensive reference to key literature and electronic databases related to mouse development*High-quality full-color production |
From inside the book
Results 1-5 of 61
Page vii
... Primitive Streak and the Organizer 44 Role of the AVE in Anterior Patterning in MOUSe 45 Embryological and Genetic Analysis Of the FUnction of the AVE in Anterior Patterning 46 Xi. A MOCe for AVE FUnction in Anterior Patterning 47 Vii ...
... Primitive Streak and the Organizer 44 Role of the AVE in Anterior Patterning in MOUSe 45 Embryological and Genetic Analysis Of the FUnction of the AVE in Anterior Patterning 46 Xi. A MOCe for AVE FUnction in Anterior Patterning 47 Vii ...
Page 2
... primitive streak, might also have roles in patterning (Kalantry et al., 2001). Some indication of the critical role of posterior visceral endoderm is highlighted by the impact of loss of Wnt3 or Hnf38 (Foxa2) activity in this tissue ...
... primitive streak, might also have roles in patterning (Kalantry et al., 2001). Some indication of the critical role of posterior visceral endoderm is highlighted by the impact of loss of Wnt3 or Hnf38 (Foxa2) activity in this tissue ...
Page 23
... primitive endoderm, another extraembryonic tissue, on its abembryonic surface. The remaining cells that occupy the region of the tissue next to the polar trophectoderm form the primitive ectoderm or epiblast, a population of cells that ...
... primitive endoderm, another extraembryonic tissue, on its abembryonic surface. The remaining cells that occupy the region of the tissue next to the polar trophectoderm form the primitive ectoderm or epiblast, a population of cells that ...
Page 25
... primitive streak formed at the onset of gastrulation. However, the notion that acquisition of bilateral symmetry is such a late event is no longer tenable. On the basis of histological analysis of blastocysts in utero, Smith (1980, 1985) ...
... primitive streak formed at the onset of gastrulation. However, the notion that acquisition of bilateral symmetry is such a late event is no longer tenable. On the basis of histological analysis of blastocysts in utero, Smith (1980, 1985) ...
Page 28
... primitive streak forms, the consequent net polar to mural flow of cells has been assumed to be radially symmetrical. However, when peripheral as opposed to central polar trophectoderm cells were lineage labeled, the resulting clones ...
... primitive streak forms, the consequent net polar to mural flow of cells has been assumed to be radially symmetrical. However, when peripheral as opposed to central polar trophectoderm cells were lineage labeled, the resulting clones ...
Contents
1 | |
Lineage Specification and Differentiation | 151 |
Organogenesis | 297 |
Author Index | 591 |
Subject Index | 691 |
Other editions - View all
Mouse Development: Patterning, Morphogenesis, and Organogenesis Janet Rossant,Patrick P. L. Tam No preview available - 2002 |
Common terms and phrases
Acad activity adult axis Biol blastocyst BMP4 bone cardiac cartilage caudal Cell Cambridge cell types chick chondrocytes craniofacial defects dermomyotome Development Cambridge developmental differentiation domain dorsal Drosophila early ectoderm embryos encoding endoderm endothelial cells epiblast epithelial epithelium fetal Fgf8 forebrain formation function gastrulation gene expression Genes Dev Genet germ cells gonad growth factor heart hematopoietic homeobox homeobox gene induce interactions lineage mammalian mesenchyme mesoderm mice lacking midline migration molecular molecules morphogenesis mouse embryo muscle mutants Myf5 MyoD myotome Natl Nature London neural crest neural tube neurons nodal oocyte organizer Otx2 paraxial pathway patterning phenotype Pitx2 plate posterior precursors primitive streak progenitors proliferation protein receptor region regulation role Rossant rostral signaling skeletal somite Sonic hedgehog Sox9 specific stage stem cells suggest telencephalon tion tissues transcription factor transgenic trophoblast ureteric bud vascular ventral vertebrate vitro vivo Xenopus yolk sac