Mouse Development: Patterning, Morphogenesis, and OrganogenesisThis book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference. *Broad-based overview of mouse development from fundamental to specialist levels*Extensive coverage of a wide range of developmental mutations of the mouse*Excellent benchmark illustrations of brain, craniofacial, gut and heart development*In-depth experiment-based assessment of concepts in mammalian development*Focus on models of specific relevance to human development*Comprehensive reference to key literature and electronic databases related to mouse development*High-quality full-color production |
From inside the book
Results 1-5 of 87
Page viii
... Ventral Patterning Involves a Tug of War between Dorsal and Ventral Signaling | 20 V. Summary | 22 References | 22 7 Somitogenesis: Segmentation of the Paraxial Mesodern and the Delineation of Tissue Compartments Achin Gossier and ...
... Ventral Patterning Involves a Tug of War between Dorsal and Ventral Signaling | 20 V. Summary | 22 References | 22 7 Somitogenesis: Segmentation of the Paraxial Mesodern and the Delineation of Tissue Compartments Achin Gossier and ...
Page 38
... ventral cell layer. Scanning electron microscopy reveals that each cell of the ventral layer of the node possesses a single large cilium on its surface (Sulik et al., 1994). Recent studies have shown that the cilia of the node generate ...
... ventral cell layer. Scanning electron microscopy reveals that each cell of the ventral layer of the node possesses a single large cilium on its surface (Sulik et al., 1994). Recent studies have shown that the cilia of the node generate ...
Page 43
... ventral patterning in the neural tube is the likely consequence of the lack of Sonic hedgehog (SHH), a signaling molecule normally expressed by the axial mesoderm that is essential for the generation and patterning of the ventral neural ...
... ventral patterning in the neural tube is the likely consequence of the lack of Sonic hedgehog (SHH), a signaling molecule normally expressed by the axial mesoderm that is essential for the generation and patterning of the ventral neural ...
Page 57
... ventral side of the node. STEP 1 STEP2 STEP3 -. -. &. --. |-. * | - ->. -\e). Vo. Vo. *ir fird, lefty- 12 int modø/ HFH-f pitr-2 A/F-3-1 || B. STEP 4 ttern R l pa heart spleen | * stomach intesrine E- flirer, liver. *. lung blood vessels - ...
... ventral side of the node. STEP 1 STEP2 STEP3 -. -. &. --. |-. * | - ->. -\e). Vo. Vo. *ir fird, lefty- 12 int modø/ HFH-f pitr-2 A/F-3-1 || B. STEP 4 ttern R l pa heart spleen | * stomach intesrine E- flirer, liver. *. lung blood vessels - ...
Page 59
... ventral side of the node have monocilia. (A) Ventral low-power view of the node. AP and L-R axes are indicated. (B) A high-power view of monocilia of the node. (Photographed by Daisuke Watanabe.) Figure 5 A comparison of the expression ...
... ventral side of the node have monocilia. (A) Ventral low-power view of the node. AP and L-R axes are indicated. (B) A high-power view of monocilia of the node. (Photographed by Daisuke Watanabe.) Figure 5 A comparison of the expression ...
Contents
1 | |
Lineage Specification and Differentiation | 151 |
Organogenesis | 297 |
Author Index | 591 |
Subject Index | 691 |
Other editions - View all
Mouse Development: Patterning, Morphogenesis, and Organogenesis Janet Rossant,Patrick P. L. Tam No preview available - 2002 |
Common terms and phrases
Acad activity adult axis Biol blastocyst BMP4 bone cardiac cartilage caudal Cell Cambridge cell types chick chondrocytes craniofacial defects dermomyotome Development Cambridge developmental differentiation domain dorsal Drosophila early ectoderm embryos encoding endoderm endothelial cells epiblast epithelial epithelium fetal Fgf8 forebrain formation function gastrulation gene expression Genes Dev Genet germ cells gonad growth factor heart hematopoietic homeobox homeobox gene induce interactions lineage mammalian mesenchyme mesoderm mice lacking midline migration molecular molecules morphogenesis mouse embryo muscle mutants Myf5 MyoD myotome Natl Nature London neural crest neural tube neurons nodal oocyte organizer Otx2 paraxial pathway patterning phenotype Pitx2 plate posterior precursors primitive streak progenitors proliferation protein receptor region regulation role Rossant rostral signaling skeletal somite Sonic hedgehog Sox9 specific stage stem cells suggest telencephalon tion tissues transcription factor transgenic trophoblast ureteric bud vascular ventral vertebrate vitro vivo Xenopus yolk sac