Mouse Development: Patterning, Morphogenesis, and Organogenesis

Front Cover
Gulf Professional Publishing, Mar 15, 2002 - Medical - 712 pages
This book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference.

*Broad-based overview of mouse development from fundamental to specialist levels
*Extensive coverage of a wide range of developmental mutations of the mouse
*Excellent benchmark illustrations of brain, craniofacial, gut and heart development
*In-depth experiment-based assessment of concepts in mammalian development
*Focus on models of specific relevance to human development
*Comprehensive reference to key literature and electronic databases related to mouse development
*High-quality full-color production

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Contents

Fertilization and Activation
5
Functional Analysis
13
Asymmetry and Prepattern
21
Asymmetry of the Blastocyst
27
Anterior Posterior Patterning of
37
Inhibitory Signals Secreted by the Organizer
44
LeftRight Asymmetry
55
Molecular Readout of
61
Concluding Remarks
228
Stem Cells of the Nervous System
235
Do Stem Cells Retain Broad or Narrow
241
Outstanding Issues
248
Specification of Muscle Fiber Types
268
Deconstructing the Molecular Biology
279
Organogenesis
297
Patterning and Differentiation of
307

VI
65
Miscellaneous Mutations
67
Patterning Regionalization and Cell
75
Establishment of AnteriorPosterior
107
Segmentation of
127
Lineage Specification
151
Comparative Aspects of Development
155
Setting Aside the Blastocyst Lineages
158
Extraembryonic Membranes
162
Germ Cells
181
Adhesive Behavior of Germ Cells
187
Current Cellular and Molecular Conceptual
205
Vasculogenesis and Angiogenesis
211
Vascular Morphogenesis
220
Perspectives and Remaining Issues
322
Molecular Determinants of Cardiac
331
Sex Determination and Differentiation
371
Testis Differentiation
380
Development of the Excretory System
395
Future Perspectives 4 16
416
SiewLan Ang 37 Michael J Depew 421
421
Pituitary Gland Development
499
Expansion of Committed Cell Types
510
Transcriptional Regulatory Systems in
519
Development of the Mouse Inner
539
Integumentary Structures
567
FollicleSpacing
577
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About the author (2002)

gregory.ginsberg.uphs.upenn.edu; Patrick T. Tam [ptt1@humboldt.edu]

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