Bilayer Lipid Membranes. Structure and Mechanical Properties

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Springer Science & Business Media, Aug 31, 1995 - Science - 436 pages
In Bilayer Lipid Membranes. Structure and Mechanical Properties the authors use new methods of measurement, which they have themselves developed, to present an analysis of the relation between membrane structure and viscoelastic properties, in particular in the transversal direction. Hianik and Passechnik's approach is fundamentally different from the usual one, in that they analyze lipid bilayer dynamics during various modes of deformation, arriving at a new, `three-layer' model that accounts for the great heterogeneity of biomembranes. The macroscopic parameters of membranes have been measured using a wide variety of methods, leading to a discussion of the correlations between the parameters. There is also an extensive discussion of the dynamic changes in mechanical properties of lipid bilayers in the course of conformational transition of integral proteins. During the conformational changes of proteins, the structure of a bilayer undergoes a transition, reaching a new, stable membrane state. The book is the first to present a comprehensive analysis of long-distance interaction in lipid bilayers and of molecular mechanisms of mechanoreception.
Audience: Scientists and graduate students working in biophysics, membranology, physiology, medicine, pharmacology, bioelectronics, electrochemistry, and colloid chemistry.

From inside the book

Contents

The elasticity and viscosity of biological membranes
1
in a transversal direction
19
55
76
Methods to measure the viscoelasticity of bilayer lipid membranes
88
The peculiarity of the electrical field in membranes and an evaluation
138
The bilayer lipid membrane as a viscoelastic body
158
The application of the phenomena of the generation of higher current
194
The mechanical properties of lipid bilayer under different action
259
The mechanical and thermodynamical properties of lipid bilayer due to
289
The distortion of the structure of lipid bilayer around membrane proteins
348
The mechanics of lipid bilayers and the problems of mechanoreception
371
Epilogue
407
Index
430
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