Inflammatory Bowel Disease: Current Status and Future Approach : Proceedings of the International Symposium on Future Research Approaches to Inflammatory Bowel Disease, Mechanisms of Chronic Infection and Inflammation, Fort Lauderdale, Florida, USA, October 7-11, 1987Richard P. MacDermott |
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Page 305
... Effects of drugs on PGE2 release were evaluated during the basal , effects on cysteinyl - LT release during the ionophore - stimulated incubation period . * For effect of SA on PGE2 formation in the presence of ionophore see results ...
... Effects of drugs on PGE2 release were evaluated during the basal , effects on cysteinyl - LT release during the ionophore - stimulated incubation period . * For effect of SA on PGE2 formation in the presence of ionophore see results ...
Page 319
... effects of LTB4 ( 0.8μg / kg ) and LTD4 ( 0.8μg / kg ) on number of spike potentials and on contractility . However , under these experimental conditions the excitatory effects of PGE2 ( 0.8μg / kg / min . ) and PGF2 ( 1.0μg / kg / min ...
... effects of LTB4 ( 0.8μg / kg ) and LTD4 ( 0.8μg / kg ) on number of spike potentials and on contractility . However , under these experimental conditions the excitatory effects of PGE2 ( 0.8μg / kg / min . ) and PGF2 ( 1.0μg / kg / min ...
Page 381
... effects . These effects were assessed using a line of human colonic epithelial cells , Tg4 . This has allowed the dissociation of effects of inflammatory mediators on intestinal secretion likely to be mediated by direct interaction with ...
... effects . These effects were assessed using a line of human colonic epithelial cells , Tg4 . This has allowed the dissociation of effects of inflammatory mediators on intestinal secretion likely to be mediated by direct interaction with ...
Contents
Defect in immunoregulatory intestinal epithelial cells in inflammatory | 9 |
Vasoactive intestinal peptide and the severity of colonic inflammation | 25 |
Substance P andor calcitonin generelated peptide are present | 43 |
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acid activity addition analysis animals antibodies antigen approach assay associated bacterial binding blood cell cultures changes chronic Clin clinical colon compared concentrations containing Crohn's disease culture cytotoxicity decreased demonstrated described detected determined Division effect epithelial cells examined experiments expression factor Figure function future Gastroenterology growth human immune Immunol increased incubated indicate induced infection inflammation inflammatory bowel disease inhibition intestinal isolated jejunum lamina propria levels lymph nodes lymphocytes MacDermott macrophages mean measured mechanisms mediators METHODS mice mucosal mycobacteria normal observed obtained occurred organisms patients positive prepared present previously production protein Publishers rats receptor REFERENCES release reported response role samples Science secretion sera serum showed shown significant similar specific specimens status stimulated strain studies suggest supported synthesis Table tested tissue ulcerative colitis vitro