In Vitro Biological SystemsCharles A. Tyson, John M. Frazier Aims to provide researchers with basic techniques employed by widely-recognized scientists in preparing and maintaining the biological components of in vitro model systems. The methods have been organized by organ systems for easy reference. |
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Page 143
... important end points can be quantitatively studied in the same system including cytoxicity , genotoxicity , and cell transformation . Another important feature of the RTE cell system is that it can be used to measure acute or chronic ...
... important end points can be quantitatively studied in the same system including cytoxicity , genotoxicity , and cell transformation . Another important feature of the RTE cell system is that it can be used to measure acute or chronic ...
Page 193
... important position in this hier- archy of defenses and has at least three important characteristics : it possesses relatively high activities of many detoxication systems , its detoxication systems are inducible , and its cells are ...
... important position in this hier- archy of defenses and has at least three important characteristics : it possesses relatively high activities of many detoxication systems , its detoxication systems are inducible , and its cells are ...
Page 417
... important issue to consider in interpret- ing the data obtained . This limitation is highlighted in work by Hottendorf ( 20 ) , who reported that the relatively nonnephrotoxic cephalosporin antibiotic cephalothin was highly toxic to LLC ...
... important issue to consider in interpret- ing the data obtained . This limitation is highlighted in work by Hottendorf ( 20 ) , who reported that the relatively nonnephrotoxic cephalosporin antibiotic cephalothin was highly toxic to LLC ...
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In Vitro Biological Systems: Methods in Toxicology, Volume 1 Charles A. Tyson,John M. Frazier Limited preview - 2016 |
Common terms and phrases
1993 by Academic Academic Press acid aliquots animals assay basal beaker Biochem Biol bovine serum buffer calcium cannula catecholamine cell cultures cell suspension cellular centrifuge tube chemical chromaffin cells Clara cells collagenase concentration containing cortical coverslips culture medium density digestion dissecting dissociation endothelial cells enzyme epithelial cells explants fetal filter flask forceps gentamicin GIBCO glucose gradient growth growth medium hepatocytes HEPES incubated inhibits isolated kidneys Kupffer cells laboratory layer lipocytes liver macrophages membrane metabolism METHODS IN TOXICOLOGY mg/ml microscope monolayer mouse neurochemical neurons obtained Pasteur pipette pellet Percoll perfusion petri dish Pharmacol pipette plastic plates preparation procedure protein proximal tubule rabbit REAGENTS reaggregates removed renal resuspended scissors segments Sigma skin slices sodium specific sterile stock solution studies supernatant tion tissue culture toxicity Toxicol trypan blue trypsin type II cells vessel viability vitro vivo Volume 1A Copyright washed µg/ml