Treatise on Pulmonary Toxicology: Comparative Biology of the Normal Lung, Volume 1

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CRC Press, Feb 21, 1992 - Medical - 848 pages
Comparative Biology of the Normal Lung is the first volume in a series entitled "A Comprehensive Treatise on Pulmonary Toxicology." The book is divided into four sections that deal with morphology and morphometry, respiratory physiology, biochemistry, and pulmonary defense. A special index lists and cross indexes all comparative data included in the text, which provides readers with easy access to a broad spectrum of pulmonary data for a number of different species. Over 50 internationally respected authors have contributed to this cutting -edge scientific study designed for all scientists concerned with the pulmonary system, including research scientists in medicine, veterinary medicine, zoology, and toxicology.

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Contents

Overview of Diversity in the Respiratory System of Mammals
Architecture of Nasal Passages and Larynx
Epithelial Cells of the Nasal Passages
Gross and Subgross Anatomy of Lungs Pleura Connective Tissue Septa Distal Airways and Structural Units
5
Architecture of the Tracheobronchial Tree
17
Epithelial Cells of Trachea and Bronchi
31
Secretory Glycoconjugates of Trachea and Bronchi
39
Epithelial Cells of Bronchioles
45
Comparative Biochemistry of the Normal Lung
277
CarbohydrateIntermediary Metabolism
279
Regulation of Antioxidant Enzyme Gene Expression in the Lung
295
Biochemistry of Lipid Mediators in the Lung
303
Comparative Biochemistry and Molecular Biology of Pulmonary Connective Tissues
327
Oxygen Metabolism in the Lungs
361
Phospholipid Composition Biosynthesis and Secretion
387
The Biology and Biochemistry of Pulmonary Alveolar Epithelial Cells
419

Secretory Proteins of Clara Cells and Type II Cells
53
Architecture of the Acinus
69
Architecture and Cellular Composition of the AirBlood Barrier
79
Basement Membrane and Extracellular Matrix
83
Kinetics of Pulmonary Cells
91
Innervation of the Lung
101
Blood Vessels of the Lung
107
Comparative Respiratory Physiology of the Normal Lung
114
Elastic Resistive and Inertial Properties of the Lung
114
Comparative Ventilation of the Normal Lung
139
Pulmonary Hemodynamics
151
Gas Exchange at Rest and During Exercise in Mammals
171
Comparative Control of Respiration
199
Aging of the Normal Lung
237
Interpretations and Limitations of Pulmonary Function Testing in Small Laboratory Animals
249
Lung Endothelial Cell Biology
427
The Biochemical Pharmacology of Pulmonary Amine Disposition
435
The Isolated Perfused Lung Preparation As A Research Tool
443
Comparative Defense Capabilities of the Respiratory Tract
469
Introduction
470
Comparative Biochemistry of Airway Lining Fluid
471
Control of Nasal and Airway Secretions Ion Transport and Water Movement
479
Mucociliary Function
503
Pulmonary Macrophage Physiology Origin Motility Endocytosis
525
Immunology of the Respiratory System
567
Antimicrobial Defense Mechanisms
589
Special Index Tables of Normal Values for Various Species
609
GENERAL INDEX
619
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References to this book

Particle Toxicology
Ken Donaldson,Paul Borm
No preview available - 2006

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