Treatise on Pulmonary Toxicology: Comparative Biology of the Normal Lung, Volume 1

Front Cover
CRC Press, Feb 21, 1992 - Medical - 848 pages
Comparative Biology of the Normal Lung is the first volume in a series entitled "A Comprehensive Treatise on Pulmonary Toxicology." The book is divided into four sections that deal with morphology and morphometry, respiratory physiology, biochemistry, and pulmonary defense. A special index lists and cross indexes all comparative data included in the text, which provides readers with easy access to a broad spectrum of pulmonary data for a number of different species. Over 50 internationally respected authors have contributed to this cutting -edge scientific study designed for all scientists concerned with the pulmonary system, including research scientists in medicine, veterinary medicine, zoology, and toxicology.

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Contents

Overview of Diversity in the Respiratory System of Mammals
Architecture of Nasal Passages and Larynx
Epithelial Cells of the Nasal Passages
3
Gross and Subgross Anatomy of Lungs Pleura Connective Tissue Septa Distal Airways and Structural Units
13
Architecture of the Tracheobronchial Tree
25
Epithelial Cells of Trachea and Bronchi
33
Secretory Glycoconjugates of Trachea and Bronchi
45
Epithelial Cells of Bronchioles
53
Comparative Biochemistry of the Normal Lung
289
CarbohydrateIntermediary Metabolism
291
Regulation of Antioxidant Enzyme Gene Expression in the Lung
307
Biochemistry of Lipid Mediators in the Lung
315
Comparative Biochemistry and Molecular Biology of Pulmonary Connective Tissues
339
Oxygen Metabolism in the Lungs
373
Phospholipid Composition Biosynthesis and Secretion
399
The Biology and Biochemistry of Pulmonary Alveolar Epithelial Cells
425

Secretory Proteins of Clara Cells and Type II Cells
61
Architecture of the Acinus
73
Architecture and Cellular Composition of the AirBlood Barrier
83
Basement Membrane and Extracellular Matrix
85
Kinetics of Pulmonary Cells
97
Innervation of the Lung
109
Blood Vessels of the Lung
114
Comparative Respiratory Physiology of the Normal Lung
115
Elastic Resistive and Inertial Properties of the Lung
117
Comparative Ventilation of the Normal Lung
139
Pulmonary Hemodynamics
159
Gas Exchange at Rest and During Exercise in Mammals
173
Comparative Control of Respiration
211
Aging of the Normal Lung
249
Interpretations and Limitations of Pulmonary Function Testing in Small Laboratory Animals
259
Lung Endothelial Cell Biology
439
The Biochemical Pharmacology of Pulmonary Amine Disposition
443
The Isolated Perfused Lung Preparation As A Research Tool
453
Comparative Defense Capabilities of the Respiratory Tract
473
Introduction
474
Comparative Biochemistry of Airway Lining Fluid
475
Control of Nasal and Airway Secretions Ion Transport and Water Movement
491
Mucociliary Function
515
Pulmonary Macrophage Physiology Origin Motility Endocytosis
537
Immunology of the Respiratory System
577
Antimicrobial Defense Mechanisms
595
Special Index Tables of Normal Values for Various Species
613
GENERAL INDEX
627
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References to this book

Particle Toxicology
Ken Donaldson,Paul Borm
No preview available - 2006

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