Free Radical Mechanisms of Tissue InjuryThis timely volume describes the contributions of free radicals and reactive oxygen species to disease processes in a variety of tissues. Topics include the roles of lipid peroxide-modified lipoproteins in atherosclerosis, peroxidation products in retinopathy, reactive oxygen species and neutrophils in mycardial ischemia-reflow injury, iron and reactive oxygen species in hemoglobin-mediated CNS damage and in asbestos-mediated lung injury. Critical reviews examine the evidence for radical species in ethanol-induced liver injury and in muscular dystrophy. The wealth of new information presented makes this book valuable for teaching and an important reference volume for researchers exploring problems in human disease. |
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activity addition adhesion alcohol alterations animals antioxidant artery asbestos associated binding Biochem Biol biological Ca2+ canine carbon tetrachloride caused cellular changes Chem chemical Clin concentrations contribute cultured damage decreased demonstrated disease effects endothelial cells endothelium enzyme ethanol evidence exposure factor fatty acids Figure formation free radicals function glutathione GSSG heart human important increased indicated induced inhibition initiation interactions intracellular Invest involved iron ischemia isolated leukocytes levels lipid peroxidation lipoprotein liver lung measurement mechanisms mediated membrane metabolism metabolites models molecules muscle muscular dystrophy myocardial myocardial infarct myocytes neutrophil normal observed occurs oxidant stress oxidation oxygen species plasma potential prevent production protection protein rabbit reactions reactive oxygen recently receptor reduced release reperfusion reperfusion injury respiratory burst response retinal role Smith species stimulated studies superoxide Table tissue tissue injury vascular vitamin vitro vivo xanthine oxidase
Bibliographic information
| Title | Free Radical Mechanisms of Tissue Injury |
| Authors | Mary Treinen Moslen, Charles V. Smith |
| Edition | illustrated |
| Publisher | CRC Press, 1992 |
| ISBN | 0849351618, 9780849351617 |
| Length | 240 pages |
| Subjects | › › Medical / Biochemistry Science / Life Sciences / Biochemistry Science / Life Sciences / Cell Biology Science / Life Sciences / Molecular Biology |
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