In Vitro Biological SystemsCharles A. Tyson, John M. Frazier Aims to provide researchers with basic techniques employed by widely-recognized scientists in preparing and maintaining the biological components of in vitro model systems. The methods have been organized by organ systems for easy reference. |
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Page 152
... mechanisms of biotransformation and toxicity to the living organism , the data may only be descriptive and provide information on late or final injury . In these instances , the investigator must hypothesize as to the actual early ...
... mechanisms of biotransformation and toxicity to the living organism , the data may only be descriptive and provide information on late or final injury . In these instances , the investigator must hypothesize as to the actual early ...
Page 157
... mechanisms of toxicity , is a complicated and a challenging issue for investigative scientists . For such drugs , a delineation must be made as to the separate contribution of each component of toxicity to the overall toxi- cological ...
... mechanisms of toxicity , is a complicated and a challenging issue for investigative scientists . For such drugs , a delineation must be made as to the separate contribution of each component of toxicity to the overall toxi- cological ...
Page 364
... mechanisms underlying selective injury in these two renal proximal tubular subdivisions following exposure to a wide va- riety of chemical agents and anoxia ( 1–3 ) . Thus far the model has been used to show that PST segments can ...
... mechanisms underlying selective injury in these two renal proximal tubular subdivisions following exposure to a wide va- riety of chemical agents and anoxia ( 1–3 ) . Thus far the model has been used to show that PST segments can ...
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In Vitro Biological Systems: Methods in Toxicology, Volume 1 Charles A. Tyson,John M. Frazier Limited preview - 2016 |
Common terms and phrases
1993 by Academic Academic Press acid aliquots animals assay basal beaker Biochem Biol bovine serum buffer calcium cannula catecholamine cell cultures cell suspension cellular centrifuge tube chemical chromaffin cells Clara cells collagenase concentration containing cortical coverslips culture medium density digestion dissecting dissociation endothelial cells enzyme epithelial cells explants fetal filter flask forceps gentamicin GIBCO glucose gradient growth growth medium hepatocytes HEPES incubated inhibits isolated kidneys Kupffer cells laboratory layer lipocytes liver macrophages membrane metabolism METHODS IN TOXICOLOGY mg/ml microscope monolayer mouse neurochemical neurons obtained Pasteur pipette pellet Percoll perfusion petri dish Pharmacol pipette plastic plates preparation procedure protein proximal tubule rabbit REAGENTS reaggregates removed renal resuspended scissors segments Sigma skin slices sodium specific sterile stock solution studies supernatant tion tissue culture toxicity Toxicol trypan blue trypsin type II cells vessel viability vitro vivo Volume 1A Copyright washed µg/ml