Fundamental NeuroscienceLarry Squire, James L. Roberts, Nicholas C. Spitzer, Michael J. Zigmond, Darwin Berg, Floyd E. Bloom, Sascha du Lac, Anirvan Ghosh, Larry R. Squire, Susan K. McConnell With over 300 training programs in neuroscience currently in existence, demand is great for a comprehensive textbook that both introduces graduate students to the full range of neuroscience, from molecular biology to clinical science, but also assists instructors in offering an in-depth course in neuroscience to advanced undergraduates. The second edition of Fundamental Neuroscience accomplishes all this and more. The thoroughly revised text features over 25% new material including completely new chapters, illustrations, and a CD-ROM containing all the figures from the text. More concise and manageable than the previous edition, this book has been retooled to better serve its audience in the neuroscience and medical communities. Key Features * Logically organized into 7 sections, with uniform editing of the content for a "one-voice" feel throughout all 54 chapters * Includes numerous text boxes with concise, detailed descriptions of specific experiments, disorders, methodological approaches, and concepts * Well-illustrated with over 850 full color figures, also included on the accompanying CD-ROM |
Contents
47 | |
Nervous System Development | 361 |
Sensory Systems | 575 |
Motor Systems | 751 |
Regulatory systems | 895 |
Behavioral and Cognitive Neuroscience | 1145 |
Permissions | 1395 |
Contributors | 1397 |
Index | 1401 |
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Common terms and phrases
AChR action potential activity afferents amino acids astrocytes axons basal binding brain Ca2+ cell body cell death cell types cellular central complex cortex cortical cytoplasmic dendritic depolarization differentiation domain dorsal electrotonic embryo enzyme ephrin-A5 excitatory expression factors fibers function G proteins G-protein GABAA receptors ganglia ganglion genes glial glucose glutamate growth cone increase inhibition inhibitory innervate inputs interactions intracellular ionotropic receptors layer mechanisms mediated membrane potential metabolic microtubules migration molecular molecules motor neurons muscle mutations myelin nerve nervous system neural crest cells neural plate neural tube Neurosci neurotransmitter NMDA NMDA receptor nucleus odor olfactory olfactory bulb organization pathway pattern peptide peripheral phosphorylation plasma membrane postsynaptic presynaptic protein kinases receptors region regulation release response retina role segment signaling specific spinal cord stimulation structure substrate subunits synaptic vesicles target taste terminal tion tissue transcription transduction transmitter transport vertebrate visual
Popular passages
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Page 151 - Nature is nowhere accustomed more openly to display her secret mysteries than in cases where she shows traces of her workings apart from the beaten path ; nor is there any better way to advance the proper practice of medicine than to give our minds to the discovery of the usual law of nature, by careful investigation of cases of rarer forms of disease.
Page 83 - Most large neurons in vertebrates are myelinated by oligodendrocytes in the CNS and by Schwann cells in the PNS. The compact wraps of myelin encasing the axon distal to the initial segment permit the rapid conduction of the action potential by a process termed "saltatory conduction
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Page 360 - Magistretti. PJ (1994). Glutamate uptake into astrocytes stimulates aerobic glycolysis: A mechanism coupling neuronal activity to glucose utilization. Proc. Natl. Acad Sci. USA 91, 10625-10629.
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Page 257 - Hollmann, M., and Heinemann, S. (1994). Cloned glutamate receptors. Annu. Rev. Neurosci. 17, 31-108.
Page 395 - Honig, MG, and Hume, RI (1986). Fluorescent carbocyanine dyes allow living neurons of identified origin to be studied in long-term cultures. J. Cell. Biol. 103, 171-187.
Page 448 - Uemura, T. (1999). Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled. Cell 98, 585-595.