The Cellular Basis of Cardiovascular Function in Health and DiseasePawan K. Singal, Vincenzo Panagia, Grant Pierce This special issue of Molecular and Cellular Biochemistry contains original research articles and review papers which were invited from the participants of a recent meeting organized to honour the 60th birthday of Naranjan S. Dhalla, Ph.D., M.D.(Hon.). The meeting, organized by Drs. Morris Karmazyn (London), Grant Pierce (Winnipeg) and Balwant Tuana (Ottawa), was held at the Best Western Lakeside Inn in Kenora, Ontario, Canada on August 23-25, 1996. The meeting was entitled The Cellular Basis of Cardiovascular Function in Health and Disease. There were over 40 invited speakers from 15 different countries represented at the meeting, attended by over 280 people. Keynote lectures were presented by Drs. Norman Alpert (Burlington, VT), Robert Jennings (Chapel Hill, NC), Makoto Nagano (Tokyo, Japan), Howard Morgan (Danville, PA), John Solaro (Chicago, IL) and Nobuskira Takeda (Tokyo, Japan). Dr. Henry Friesen, President of the Medical Research Council of Canada, presented Dr. Dhalla with a plaque at the banquet honouring his research accomplishments over his distinguished career. Dr. Dhalla's outstanding research achievements in understanding the subcellular basis of cardiovascular disease were highlighted at the meeting. One of the unique aspects of the meeting was the special effort made by 39 former trainees of Dr. Dhalla to attend the meeting to honour their mentor. The ex-students and trainees came from all over Canada, the United States, Japan, Slovakia, Germany, the Czech Republic, Estonia and the Netherlands. The meeting was judged to be an overwhelming success in terms of the scientific content as well as collaborative interactions initiated. |
Contents
VASCULAR CHANGES IN HEALTH AND DISEASE | 3 |
Analysis of responses to human synthetic adrenomedullin and calcitonin generelated peptides in the hindlimb vascular bed of the cat | 5 |
Intimal hyperplasia reendothelialization and attenuation of endothelialdependent relaxation | 13 |
Differential regulation of Gprotein expression by vasoactive peptides | 21 |
Receptor types and Ca2+mobilization | 29 |
Activation of the neutrophil and loss of plasma glutathione during Mgdeficiency modulation by nitric oxide synthase inhibition | 35 |
Velocity of translation of single actin filaments AF by myosin heads from antigensensitized airway smooth muscle | 41 |
Smooth muscle contractility and protein tyrosine phosphorylation | 47 |
SUBCELLULAR CHANGES IN CARDIOMYOPATHIES AND HEART FAILURE | 155 |
Changes in fatty acid compositions of myocardial lipids in rats with heart failure following myocardial infarction | 161 |
Mechanisms that may be involved in calcium tolerance of the diabetic heart | 167 |
Increases of Ttype Ca2+ current in heart cells of the cardiomyopathic hamster | 172 |
Influence of beta blocking agents | 175 |
Phosphorylation by protein kinase C and the responsiveness of Mg2+ATPase to Ca2+ of myofibrils isolated from stunned and nonstunned porcine m... | 181 |
Is there a link between impaired glucose metabolism and protein kinase C activity in the diabetic heart? | 187 |
Experimental myocardial infarction in rats in vivo with reduced mortality | 193 |
Migration of heterogeneous cell populations from vessel wall | 53 |
An overview of the influence of ACE inhibitors on fetalplacental circulation and perinatal development | 61 |
CARDIAC MECHANISMS IN HEALTH | 73 |
Differential nature of crosstalk among three Gcoupled receptors regulating adenylyl cyclase in rat cardiomyocytes chronically exposed to receptor ag... | 75 |
Reversal of phosphate induced decreases in force by the benzimidazole pyridazinone UDCG 212 CL in myofilaments from human ventricle | 81 |
Expression of fibroblast growth factor receptor1 in rat heart H9c2 myoblasts increases cell proliferation | 87 |
Identification of an HMGlike protein involved in regulation of Na+H+ exchanger expression | 95 |
Cytochemical and immunocytochemical localization of NaKATPase α subunit isoenzymes in the rat heart | 103 |
Estradiol modulates the sodium pump in the heart sarcolemma | 109 |
Thyroid hormones differentially affect sarcoplasmic reticulum function in rat atria and ventricles | 115 |
Dietary and physiological studies to investigate the relationship between calcium and magnesium signalling in the mammalian myocardium | 121 |
Biological significance of phosphorylation and myristoylation in the regulation of cardiac muscle proteins | 126 |
Contributions of increased efficiency and capacity of protein synthesis to rapid cardiac growth | 133 |
Movement from chromosomal to cleavage furrow and midbodyassociated sites | 141 |
Its effects on sarcoplasmic reticular SR Ca2+ metabolism | 149 |
Adriamycin depresses in vivo and in vitro phosphatidylethanolamine Nmethylationin rat heart sarcolemma | 199 |
A calcium stimulated cysteine protease involved in isoproterenol induced cardiac hypertrophy | 203 |
Early fetal like slow Na+ current in heart cells of cardiomyopathic hamster | 209 |
Na+H+ exchange inhibition at reperfusion is cardioprotective during myocardial ischemiareperfusion 31P NMR studies | 217 |
Increased gene expression of plasminogen activators and inhibitors in left ventricular hypertrophy | 223 |
Old concepts new perspectives | 231 |
Effect of diabetes mellitus | 237 |
Role of free radicals | 243 |
Ischemic preconditioning is not additive to preservation with hypothermia or crystalloid cardioplegia in the globally ischemic rat heart | 253 |
CELLULAR BIOCHEMISTRY IN NONCARDIOVASCULAR TISSUES | 261 |
Regulation of Ca2+ homeostasis by glucose metabolism in rat brain | 263 |
LAcp corpulent rat | 273 |
Studies on hepatic injury and antioxidant enzyme activities in rat subcellular organelles following in vivo ischemia and reperfusion | 283 |
Other editions - View all
The Cellular Basis of Cardiovascular Function in Health and Disease Pawan K. Singal,Vincenzo Panagia,Grant Pierce No preview available - 2012 |
The Cellular Basis of Cardiovascular Function in Health and Disease Pawan K. Singal,Vincenzo Panagia,Grant Pierce No preview available - 2011 |
Common terms and phrases
ACE inhibitors adenylyl cyclase angiotensin animals antioxidant antioxidant enzyme aortic assay ATPase atria Bevantolol binding Biol Chem buffer Ca² Ca2+ uptake calcium calpain cardiac cardiomyocytes cardiomyopathy cardioplegia cellular Circ Res contractile coronary artery cp/cp decreased diabetic heart dp/dt effects enzyme EPIF factor fatty acid fetal fraction free radical function gene glucose glutathione hamster heart cells hepatic hormones hypertrophy hypothyroid increased infarction inhibition injury inotropic insulin intracellular ischemia ischemia/reperfusion ischemic isoforms isolated isoproterenol left ventricle left ventricular levels lipid membrane metabolism Mg2+ mitochondrial Mol Cell Biochem Molecular mRNA myocardial myocardial infarction myocardium myocytes myofibrils myosin Na,K-ATPase NTPase activity nuclear nuclei oxidative stress perfusion peroxisomes Pharmacol phosphorylation Physiol plasma preconditioning pressure Propranolol protein kinase rat heart receptor regulation reperfusion response role sarcolemma sarcoplasmic sarcoplasmic reticulum significant significantly smooth muscle stimulation subcellular synthesis thyroid tissue vascular