Function & Dysfunction in the Nervous System

Front Cover
CSHL Press, 1996 - Medical - 875 pages
Much is being learned about how the brain works by studies of diseases that affect it. This volume portrays aspects of neuroscience today - language development, visual awareness, neuronal plasticity, sensory perception, memory formation - by presenting studies on their normal mechanisms alongside investigations of abnormalities caused by degenerative disease, addiction, developmental errors, and other maladies. In this volume over 80 of the world's investigators discuss their perspectives.

From inside the book

Contents

Neuregulins as Potential Drugs for Neurological Disorders M A Marchionni C
471
Theoretical Spectroscopic and Genet
495
The Role of PrP in Pathogenesis of Experimental Scrapie C Weissmann M Fischer
511
Abnormal Plasma Membrane Properties and Functions in Prioninfected Cell Lines
531
The Role of Presenilin 1 in the Genetics of Alzheimers Disease R F Clark M Hutton
551
Molecular Dissection of the Neurofibrillary Lesions of Alzheimers Disease M
565
Cell Biology of the BAmyloid Precursor Protein and the Genetics of Alzheimers
587
Discussion of Molecular Mechanism C T Caskey M S Swanson
607

Olfactory Recognition and Discrimination in Caenorhabditis elegans J H Chou E
157
Biochemical and Transgenic Analysis of Gustducins Role in Bitter and Sweet Trans
173
Neural Mechanisms of Declarative Memory H Eichenbaum J Dusek B Young
197
CaMKII Function in the Nervous System Explored from a Genetic Perspective M
219
Genetic Analysis of Function and Dysfunction in the Central Nervous System A
239
Converging Evidence from Infra
259
Molecular Anatomy of a Lightsensitive Circadian Pacemaker in Drosophila M
279
Forward Genetic Approaches to Circadian Clocks in Mice D P King and J S Takahashi
295
Multiple Myosin Isozymes and Haircell Function P G Gillespie T Hasson J A Gar
316
Molecular and Genetic Insights into Ligand Binding and Signal Transduction at
333
Assembly
363
Neuronal Survival and Signaling
385
Nitric Oxide Cell Multiplication and Cell Survival N Peunova B Kuzin I Roberts
417
The Role of Neuregulin ARIA at the Neuromuscular Junction K M Rosen A
427
GDNF Is Required for Kidney Development and Enteric Innervation J G Pichel L
445
Targeted Inactivation of the Mouse Huntingtons Disease Gene Homolog Hdh M
627
Toward Understanding Polyglutamineinduced Neurological Disease in Spinocerebellar
649
Connexin32 and Xlinked CharcotMarieTooth Disease K H Fischbeck S M Des
673
Molecular Characterization of the Protein Products of the Fragile X Syndrome Gene
689
Neurofilaments Radial Growth of Axons and Mechanisms of Motor Neuron Disease
709
Neurodegenerative Diseases and Model Systems D L Price D R Borchelt P C Wong
725
Extracellular Proteases in Neuronal Function and Degeneration S Strickland
739
Dementia Addiction and Psychiatric Diseases
759
Recent Developments in the Genetics of Bipolar Disorder J R DePaulo Jr and F
783
An Epidemiologic
797
Molecular Genetic Studies of Schizophrenia P McGuffin and M J Owen
815
Genotype and Phenotype Analysis at the 22q11 Schizophrenia Susceptibility Locus M
835
Function and Dysfunction of the Nervous System Z W Hall
851
Subject Index
865
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Page 302 - Simon, M. (1992) Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector.
Page 425 - Greene, LA, and Tischler, AS (1976). Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.
Page 426 - Oltvai, ZN, Milliman, CL, and Korsmeyer, SJ (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74, 609-619.
Page 492 - Deng. Z. Rahmani. A. Krizus. D. McKenna-Yasek, A. Cayabyab. SM Gaston. R. Berger. RE Tanzi, JJ Halperin, B. Herzfeldt, R. Van den Bergh, W.-Y. Hung, T. Bird, G. Deng. DW Mulder. C. Smyth, NG Laing, E. Soriano, MA Pericak- Vance.
Page 223 - Gossen, M. and Bujard, H. (1992) Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.
Page 74 - This work was partly supported by the Ministry of Education. Science and Culture of Japan. the Ministry of Health and Welfare of Japan, the Uehara Memorial Foundation and the Sankyo Foundation of Life Science.
Page 413 - A novel protein that interacts with the death domain of Fas/APOl contains a sequence motif related to the death domain. J Biol Chem 270: 7795-7798 34 Chinnaiyan AM.
Page 359 - Institut National de la Sante et de la Recherche Medicale...
Page 306 - Jan, and L. Evans. 1979. Synaptic vesicle exocytosis captured by quick freezing and correlated with quanta!